Results 281 to 290 of about 235,236 (395)

Loss of TRPV4 is insufficient to promote repair in a spinal cord injury contusion model. [PDF]

Sci Rep
Mertens M, Kessels S, Veeningen N, Scheijen EEM, Mussen F, Delbroek A, Van Broeckhoven J, Alpizar YA, Brône B.   +8 more
europepmc   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice. [PDF]

Nat Commun
Gao X, Zhang J, Zhang H, Liu X, Zeng B, Wang H, Zhang H, Lui WO, Hui X, Miao H, Li J.   +10 more
europepmc   +1 more source

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators.

Blood, 2012
Jesmond Dalli, C. Serhan
semanticscholar   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Transferrin knockout reveals a tolerance phenotype against Piscirickettsia salmonis in Atlantic salmon phagocytes. [PDF]

Vet Res
Mejías M, Sáez A, Escorza A, Galdames-Contreras F, Jin Y, Dettleff P, Ojeda I, Pulgar R, Escobar-Aguirre S.   +8 more
europepmc   +1 more source

Endogenous Repair in Vanishing White Matter

Annals of Neurology, EarlyView.
Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in the deep gray structures and brainstem.
Bonnie C. Plug, Jodie H.K. Man, Marjolein Breur, Erik Nutma, Menno D. Stellingwerff, Truus E.M. Abbink, Marianna Bugiani, Marjo S. van der Knaap   +7 more
wiley   +1 more source

A multivalent capsule vaccine protects against Klebsiella pneumoniae bloodstream infections in healthy and immunocompromised mice. [PDF]

NPJ Vaccines
Wantuch PL, Robinson LS, Knoot CJ, Darwech I, Matsuguma AM, Vinogradov E, Scott NE, Harding CM, Rosen DA.   +8 more
europepmc   +1 more source

Differential endocytotic characteristics of a novel human B/DC cell line HBM‐Noda: effective macropinocytic and phagocytic function rather than scavenging function

, 2001
Ikuko Torii, Shigeru Morikawa, Makoto Nagasaki, Akinobu Nokano, Keiko Morikawa   +4 more
openalex   +1 more source

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source