Results 31 to 40 of about 235,236 (395)

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis

Frontiers in Immunology, 2020
Invertebrates generally lack adaptive immunity and compensate for this with highly efficient innate immune machineries such as phagocytosis by hemocytes to eradicate invading pathogens.
Yue Lin, Yue Lin, Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Haitao Ma, Haitao Ma, Haitao Ma, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Shu Xiao, Shu Xiao, Shu Xiao, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu   +30 more
doaj   +1 more source

The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

Frontiers in Cellular and Infection Microbiology, 2023
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism.
Aryashree Arunima, Erin J. van Schaik, James E. Samuel   +2 more
doaj   +1 more source

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

Immunometabolism of Phagocytes and Relationships to Cardiac Repair

Frontiers in Cardiovascular Medicine, 2019
Cardiovascular disease remains the leading cause of death worldwide. Myocardial ischemia is a major contributor to cardiovascular morbidity and mortality.
Shuang Zhang, Gael Bories, Connor W. Lantz, R. Emmons, Amanda C Becker, Esther Liu, M. Abecassis, L. Yvan-Charvet, E. Thorp   +8 more
semanticscholar   +1 more source

Biosynthesis of DNA for disease detection.

Jurnal Mangifera Edu
An aquatic plant breathes through pores in the atmosphere, creating a bacterial loop cycle. Harmful toxins and pathogens invade the foreign substrate and recessive genes.
Nur Aifiah Binti Ibrahim
doaj   +1 more source

Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis [PDF]

, 2016
TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative therapies for these diseases.
Barrios, Bibiana Elisabet, Correa, Silvia Graciela, De Paula Silva, Marina, Maccio Maretto, Lisa, Oliani, Sonia María, Poliselli Farsky, Sandra Helena, Sena, Angela   +6 more
core   +1 more source

Immunometabolism of Phagocytes During Mycobacterium tuberculosis Infection

Frontiers in Molecular Biosciences, 2019
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer among infectious diseases worldwide. The nature of the host immune response dictates whether the initial Mtb infection is cleared or progresses toward active ...
Ranjeet Kumar, Pooja Singh, Afsal Kolloli, Lanbo Shi, Y. Bushkin, Sanjay Tyagi, S. Subbian   +6 more
semanticscholar   +1 more source

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes—Activation and Age-Related Effects

Frontiers in Immunology, 2018
In the central nervous system (CNS), microglia are innate immune mononuclear phagocytes (CNS MPs) that can phagocytose infectious particles, apoptotic cells, neurons, and pathological protein aggregates, such as Aβ in Alzheimer’s disease (AD).
S. Rangaraju, S. Raza, N. Li, R. Betarbet, E. Dammer, D. Duong, J. Lah, N. Seyfried, A. Levey   +8 more
semanticscholar   +1 more source

The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of Yersinia pestis

Pathogens, 2020
Yersinia pestis, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must adapt to a wide range of host environments to achieve successful
Hana S. Fukuto, Gloria I. Viboud, Viveka Vadyvaloo   +2 more
doaj   +1 more source

CFTR Modulators Dampen Aspergillus-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes

Frontiers in Cellular and Infection Microbiology, 2020
Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A.
Alexander J. Currie, Alexander J. Currie, Ellen T. Main, Heather M. Wilson, Darius Armstrong-James, Adilia Warris   +5 more
doaj   +1 more source