Results 31 to 40 of about 219,012 (412)

To stimulate the phagocytes [PDF]

open access: yesBlood, 2015
“There is at bottom only one genuinely scientific treatment for all diseases, and that is to stimulate the phagocytes.” We have come a long way since this declamation by Sir Ralph Bloomfield Bonington in George Bernard Shaw’s 1906 play, The Doctor’s Dilemma.
openaire   +4 more sources

Phagocytic Uptake ofEncephalitozoon cuniculiby Nonprofessional Phagocytes [PDF]

open access: yesInfection and Immunity, 2000
ABSTRACTEncephalitozoon cuniculiis an obligate intracellular, spore-forming parasite belonging to the microsporidia that can cause disseminated infection in immunocompromised persons.E. cuniculispores infect host cells by germination, i.e., by explosively everting the polar filament, through which the spore contents (sporoplasms) are subsequently ...
Elisabeth Cejas   +5 more
openaire   +3 more sources

Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity

open access: yesFrontiers in Immunology, 2019
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques.
Alwin Kamermans   +5 more
doaj   +1 more source

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

open access: yesNature Communications, 2018
Clearance of invading microbes requires phagocytes of the innate immune system. However, successful pathogens have evolved sophisticated strategies to evade immune killing.
L. Kasper   +10 more
semanticscholar   +1 more source

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney [PDF]

open access: yes, 2017
Tamm-Horsfall protein (THP), also known as uromodulin, is a kidney-specific protein produced by cells of the thick ascending limb of the loop of Henle. Although predominantly secreted apically into the urine, where it becomes highly polymerized, THP is ...
Dagher, Pierre C.   +12 more
core   +1 more source

Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

open access: yesNature Communications, 2017
Astrocytes become reactive following various brain insults; however, the functions of reactive astrocytes are poorly understood. Here, we show that reactive astrocytes function as phagocytes after transient ischemic injury and appear in a limited ...
Yosuke M. Morizawa   +11 more
semanticscholar   +1 more source

Focusing on Phagocytes [PDF]

open access: yesDevelopmental Cell, 2016
2016 marks the centenary of the death of Elie Metchnikoff, whose 19th-century studies of starfish larvae led to the description of immune cell phagocytosis. This discovery, along with follow-up studies, earned Metchnikoff the 1908 Nobel Prize in Physiology or Medicine. We have come a long way since those early discoveries. A hundred years later, we now
openaire   +3 more sources

New Data on the Rhamnose-Binding Lectin from the Colonial Ascidian Botryllus schlosseri: Subcellular Distribution, Secretion Mode and Effects on the Cyclical Generation Change

open access: yesMarine Drugs, 2023
Botryllus schlosseri in a cosmopolitan ascidian, considered a reliable model organism for studies on the evolution of the immune system. B. schlosseri rhamnose-binding lectin (BsRBL) is synthesised by circulating phagocytes and behaves as an opsonin by ...
Giacomo Bovo, Loriano Ballarin
doaj   +1 more source

<em>Bacillus anthracis</em> Factors for Phagosomal Escape

open access: yesToxins, 2012
The mechanism of phagosome escape by intracellular pathogens is an important step in the infectious cycle. During the establishment of anthrax, <em>Bacillus anthracis</em> undergoes a transient intracellular phase in which spores are engulfed
Irene Zornetta, Fiorella Tonello
doaj   +1 more source

Pseudomonas aeruginosa biofilm is a potent inducer of phagocyte hyperinflammation [PDF]

open access: yes, 2019
Objective Pseudomonas aeruginosa effectively facilitate resistance to phagocyte killing by biofilm formation. However,b the cross talk between biofilm components and phagocytes is still unclear.
Chain, Benjamin M.   +9 more
core   +2 more sources

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