Results 41 to 50 of about 86,040 (309)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Revista Brasileira de Plantas Medicinais, 2012 O objetivo deste trabalho foi avaliar a atividade funcional de macrófagos de ratos diabéticos, através da liberação do ânion superóxido, na presença do composto "mais vida".
E.L. França +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The Response of Phagocytes Indoor Air Toxicity [PDF]
, 2022 This perspective presents a viewpoint on potential methods assessing toxicity of indoor air. Until recently, the major techniques to document moldy environment have been microbial isolation using conventional culture techniques for fungi and bacteria as ...
Vilen LK, Atosuo J, Lilius EM
core +1 more source
Neutrophil extracellular traps and their role in health and disease
South African Journal of Science, 2016 The human innate immune system is indispensable for protection against potentially invasive microbial and viral pathogens, either neutralising them or containing their spread until effective mobilisation of the slower, adaptive (specific), immune ...
Jan G. Nel +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The trajectory and characteristics of mononuclear phagocytes’ differentiation into macrophages. [PDF]
(A). Pseudotime plot showed the dynamics of mononuclear phagocytes. (B). Pseudotime plot of mononuclear phagocytes showed stages of each cluster. (C). Developmental trajectory of mononuclear phagocytes inferred by RNA velocity.
Jinyun Chen (264711) +7 more
core +1 more source
Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes [PDF]
, 2017 NRAMP1 (SLC11A1) is a professional phagocyte membrane importer of divalent metals that contributes to iron recycling at homeostasis and to nutritional immunity against infection. Analyses of data generated by several consortia and additional studies were
Mathieu Cellier +3 more
core +1 more source
Signaling of nicotinic acetylcholine receptors in mononuclear phagocytes [PDF]
, 2023 Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system.
Veronika Grau, Katrin Richter
core +1 more source
Self-DNA Sensing by cGAS-STING and TLR9 in Autoimmunity: Is the Cytoskeleton in Control?
Frontiers in Immunology, 2021 Modified or misplaced DNA can be recognized as a danger signal by mammalian cells. Activation of cellular responses to DNA has evolved as a defense mechanism to microbial infections, cellular stress, and tissue damage, yet failure to control this ...
Roberto Amadio +3 more
doaj +1 more source