Results 41 to 50 of about 91,899 (296)
Frontiers in Immunology, 2020 Invertebrates generally lack adaptive immunity and compensate for this with highly efficient innate immune machineries such as phagocytosis by hemocytes to eradicate invading pathogens.
Yue Lin +30 more
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Frontiers in Cellular and Infection Microbiology, 2023 The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism.
Aryashree Arunima +2 more
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Annals of the New York Academy of Sciences, 1997 Activation of lung phagocytes, whether involving residential or recruited phagocytic cells (macrophages, monocytes, neutrophils), results in a series of products important for development of inflammatory injury of the lung. An understanding of the mechanisms of cell activation as well as how products of these activated cells interact with cellular and ...
openaire +3 more sources
The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of Yersinia pestis
Pathogens, 2020 Yersinia pestis, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must adapt to a wide range of host environments to achieve successful
Hana S. Fukuto +2 more
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Química NovaThe aim of this study was to develop and characterize a Brazil nut oil microemulsion system and determine the effect of this microemulsion on the superoxide release in human phagocytes.
Karol Patel Fiori +8 more
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Frontiers in Cellular and Infection Microbiology, 2020 Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A.
Alexander J. Currie +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Revista Brasileira de Plantas Medicinais, 2012 O objetivo deste trabalho foi avaliar a atividade funcional de macrófagos de ratos diabéticos, através da liberação do ânion superóxido, na presença do composto "mais vida".
E.L. França +3 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Neutrophil extracellular traps and their role in health and disease
South African Journal of Science, 2016 The human innate immune system is indispensable for protection against potentially invasive microbial and viral pathogens, either neutralising them or containing their spread until effective mobilisation of the slower, adaptive (specific), immune ...
Jan G. Nel +5 more
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