Results 31 to 40 of about 140,162 (306)

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Microbiology Spectrum, 2023
Mycobacterium abscessus, an intracellular nontuberculous mycobacterium, is considered the most pathogenic species among the group of rapidly growing mycobacteria. The resistance of M. abscessus to the host innate response contributes to its pathogenicity
Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski   +5 more
doaj   +1 more source

RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]

, 2017
Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L, Hole, Camaron R, Khader, Shabaana A, Srikanta, Deepa, Williams, Matthew   +4 more
core   +2 more sources

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis

Frontiers in Immunology, 2020
Invertebrates generally lack adaptive immunity and compensate for this with highly efficient innate immune machineries such as phagocytosis by hemocytes to eradicate invading pathogens.
Yue Lin, Yue Lin, Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Haitao Ma, Haitao Ma, Haitao Ma, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Shu Xiao, Shu Xiao, Shu Xiao, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu   +30 more
doaj   +1 more source

The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

Frontiers in Cellular and Infection Microbiology, 2023
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism.
Aryashree Arunima, Erin J. van Schaik, James E. Samuel   +2 more
doaj   +1 more source

Phagocytes and the Lung [PDF]

Annals of the New York Academy of Sciences, 1997
Activation of lung phagocytes, whether involving residential or recruited phagocytic cells (macrophages, monocytes, neutrophils), results in a series of products important for development of inflammatory injury of the lung. An understanding of the mechanisms of cell activation as well as how products of these activated cells interact with cellular and ...
openaire   +3 more sources

The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of Yersinia pestis

Pathogens, 2020
Yersinia pestis, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must adapt to a wide range of host environments to achieve successful
Hana S. Fukuto, Gloria I. Viboud, Viveka Vadyvaloo   +2 more
doaj   +1 more source

MICROEMULSION OF BRAZIL NUT OIL AS A NATURAL PRODUCT TO IMPROVE SUPEROXIDE RELEASE IN HUMAN PHAGOCYTES

Química Nova
The aim of this study was to develop and characterize a Brazil nut oil microemulsion system and determine the effect of this microemulsion on the superoxide release in human phagocytes.
Karol Patel Fiori, Maycon de Paula Ribeiro Torres, Jessica Iara Schons, Elton Brito Ribeiro, Roberta Martins Nogueira, Leonardo G. Vasconcelos, Carla R. Andrighetti, Marcos José Jacinto, Denia M. de S. Valladão   +8 more
doaj   +1 more source

CFTR Modulators Dampen Aspergillus-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes

Frontiers in Cellular and Infection Microbiology, 2020
Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A.
Alexander J. Currie, Alexander J. Currie, Ellen T. Main, Heather M. Wilson, Darius Armstrong-James, Adilia Warris   +5 more
doaj   +1 more source

What makes gouty inflammation so variable? [PDF]

, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core   +2 more sources

Subversion of host innate immunity by uropathogenic Escherichia coli [PDF]

, 2016
Uropathogenic Escherichia coli (UPEC) cause the majority of community-onset urinary tract infections (UTI) and represent a major etiologic agent of healthcare-associated UTI.
Cavalieri, Godaly, Hagberg, Hedges, Schappert, Shahin   +5 more
core   +3 more sources