Results 231 to 240 of about 273,745 (349)
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong+16 more
wiley +1 more source
Measurement of macrophage phagocytic capacity by quantifying maximum membrane extension using an opsonized capillary tube assay. [PDF]
Horonushi D+4 more
europepmc +1 more source
Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang+10 more
wiley +1 more source
Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis. [PDF]
Xu Y+11 more
europepmc +1 more source
Supramolecular Lubricating Hydrogel Microspheres Reshape Damaged Matrix Regeneration
The supramolecular lubricating hydrogel microspheres can provide stable mechanophysical protection at damaged matrix through interfacial hydration lubrication: in the early and middle stages, microspheres can actively provide microscale supramolecular lubrication (µ ≈ 0.04) for damaged matrix; in the late stage, the wear debris induced by shear and ...
Hui Yuan+3 more
wiley +1 more source
The role of opsonophagocytosis in killing of <i>Klebsiella pneumoniae</i> in human blood. [PDF]
Hymøller CM+5 more
europepmc +1 more source
Theranostic Toolbox for Neutrophil Functionalization
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain+11 more
wiley +1 more source
Chemoradiation-Altered Micromilieu of Glioblastoma Cells Particularly Impacts M1-like Macrophage Activation. [PDF]
Shojaei M+5 more
europepmc +1 more source