Results 231 to 240 of about 435,809 (335)

Older female mice lacking triggering recepter expressed on myeloid cells-2 have worse post-stroke neurological function and enhanced pro-inflammatory responses [PDF]

, 2019
Hsieh, C, Kacimi, R, Kurisu, K, Yenari, MA, Zheng, Z   +4 more
core  

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Effect of periostin (OSF-2) on phagocytosis of <i>Plasmodium</i>-infected erythrocytes. [PDF]

Front Microbiol
Chin JY, Mohammed-Syafiei MN, Lim YJ, Chong GX, Suhaimi MN, Phong ZY, Ng YL, Lau YL, Sam IC, Rénia L, Lee WC.   +10 more
europepmc   +1 more source

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin

Nature, 2017
Jun Chen, Ming-Chao Zhong, Huaijian Guo, Dominique Davidson, Sabrin Mishel, Yan Lu, Inmoo Rhee, Luis-Alberto Pérez-Quintero, Shaohua Zhang, M. Cruz-Munoz, Ning Wu, D. Vinh, M. Sinha, V. Calderon, C. Lowell, J. Danska, A. Veillette   +16 more
semanticscholar   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Fungal immunomodulatory proteins skew macrophages towards a pro-inflammatory and tumour inhibitory phenotype. [PDF]

Cancer Immunol Immunother
Liu Y, Krzysica PA, Li Z, Wichers HJ, Bastiaan-Net S, Hoppenbrouwers T.   +5 more
europepmc   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

Advanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou, Ke Li, Xuelan Li, Lei Yi, Zhengxiang Wang, Huan Ding, Sheng Wu, Feiyu Liu, Yuan Li, Rui Cheng, Jianliang Shen   +10 more
wiley   +1 more source

Efferocytosis: Gateway for tissue resolution. [PDF]

J Cereb Blood Flow Metab
Cho S, Ju H.
europepmc   +1 more source

Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries

Advanced Science, EarlyView.
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao, Jianfeng Liu, Jincheng Li, Di Li, Jianxun Ding, Bin Liu   +5 more
wiley   +1 more source

PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids. [PDF]

Brain
Ljubikj T, Mars MZ, van der Geest AT, Jakobs CE, Bessler N, Donega V, van den Oetelaar XPRM, de Wit M, Pasterkamp RJ.   +8 more
europepmc   +1 more source