Results 231 to 240 of about 264,616 (357)

A novel Pyroptosis‐related long non‐coding RNA signature for predicting the prognosis and immune landscape of head and neck squamous cell carcinoma

open access: yesCancer Medicine, Volume 11, Issue 24, Page 5097-5112, December 2022., 2022
our findings robustly demonstrate that our constructed prlncRNA signature could serve as an efficient indicator of prognosis, immunotherapy response, and chemosensitivity for HNSCC patients. Abstract Background Pyroptosis plays an essential function in carcinogenesis and the antitumor immune response.
Chongchang Zhou   +6 more
wiley   +1 more source

Early secretory antigen target of 6-kDa of Mycobacterium tuberculosis inhibits macrophage apoptosis and host defense via TLR2. [PDF]

open access: yesRespir Res
Zhang L   +17 more
europepmc   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang   +5 more
wiley   +1 more source

Exosomes and their roles in the chemoresistance of pancreatic cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan   +4 more
wiley   +1 more source

Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy. [PDF]

open access: yesFront Immunol
Krishnamoorthy M   +14 more
europepmc   +1 more source

Phagocytosis of apoptotic cells in homeostasis

open access: yesNature Immunology, 2015
S. Arandjelovic, K. Ravichandran
semanticscholar   +1 more source

Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Engineered Mn‐substituted HfO2 (HMO) is identified with enhanced sonopiezoelectric effects and multienzymatic activities, promoting reactive oxygen species generation and amplifying oxidative stress in cancer cells. Upon ultrasound irradiation, HMO evokes cancer cell PANoptosis, thereby triggering robust antitumor immunity.
Linhong Zhong   +9 more
wiley   +1 more source

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