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Phagocytosis

2022
One hundred years have passed since the death of Élie Metchnikoff (1845-1916). He was the first to observe the uptake of particles by cells and realized the importance of this process, named phagocytosis, for the host response to injury and infection. He also was a strong advocate of the role of phagocytosis in cellular immunity, and with this, he gave
Eileen, Uribe-Querol, Carlos, Rosales
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Phagocytosis

BioEssays, 1995
AbstractPhagocytosis is the process of recognition and engulfment of microorganisms or tissue debris that accumulate during infection, inflammation or wound repair. This ingestion, which is performed most efficiently by migrating, bone marrow‐derived cells called ‘professional phagocytes’, is essential for successful host defense.
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Specialization in phagocytosis

Journal of Theoretical Biology, 1976
Abstract When phagocytes have been incubated with a mixture of two types of particles (say A and B), a microscopic count can be made of cells having ingested i A-particles and j B-particles, for various i and j. Simple assumptions (the validity of which has been checked in a previous work) allow derivation of formulae that give a fair account of ...
P, Bongrand   +3 more
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Phagocytosis by neutrophils

Microbes and Infection, 2003
Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Warren L, Lee   +2 more
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Antibiotics and Phagocytosis

European Journal of Clinical Microbiology, 1983
The influence of beta-lactam antibiotics, tetracyclines, aminoglycosides, erythromycin and clindamycin on the phagocytosis process is reviewed. The results of the studies published are summarized in tabular form.
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Mechanisms of phagocytosis

Current Opinion in Immunology, 1996
Recent advances in research on phagocytosis include a better appreciation of the cross-talk between phagocytic receptors, the definition of multiple signaling domains within these receptors, and a deeper understanding of the downstream effector pathways leading to actin polymerization and particle internalization.
L A, Allen, A, Aderem
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An Introduction to Phagocytosis

2020
Phagocytosis is usually defined as the cellular process by which cells internalise particulate matter larger than about 0.5 μm in diameter. It is an endocytic process, distinct from pinocytosis and macropinocytosis. These latter processes may internalise small particles suspended the extracellular fluid, but this is a by-product of internalising the ...
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PHAGOCYTOSIS IN INVERTEBRATES

Australian Journal of Experimental Biology and Medical Science, 1968
SummaryTwo species of invertebrates, Parachaeraps bicarinatus, a freshwater crayfish, and Helix pomatia, a garden snail, were examined for the presence of cells which could phagocytose particulate material introduced into their vascular systems. By means of blood clearance studies and histological techniques, it was demonstrated that there existed a ...
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Phagocytosis: A Review

CRC Critical Reviews in Toxicology, 1978
Primitive unicellular organisms depend greatly on internalization of particulate matter for nourishment. In metazoa, this process is further developed to play a major role in mechanisms of defense. This review analyzes, mainly in mammalian systems, the various phenomena surrounding the phagocytic act. Much of the emphasis is placed on experimental work
M. N.-I. Walters   +2 more
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