Results 71 to 80 of about 396,432 (395)
Chimeric antigen receptors that trigger phagocytosis
bioRxiv, 2018 Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T cells to kill cancer. The success of CAR-T cell therapies highlights the promise of programmed immunity, and suggests that applying CAR strategies to other immune cell lineages ...
Meghan A. Morrissey +6 more
semanticscholar +1 more source
Research progress of astrocyte phagocytosis in Alzheimer′s disease [PDF]
Jichu yixue yu linchuangAstrocytes are heavily activated in Alzheimer′s disease, engulfing damaged synapses, Aβ proteins, Tau proteins, apoptotic cells and other substrates. However, these substrates are difficult to degrade, accumulate as the disease progresses, and impair the
QIN Xiaoli, ZHAO Linna, FU Rong, GUO Yuying, XU Shixin
doaj +1 more source
Journal of Immunology Research, 2021 We recently showed that both nontypeable Haemophilus influenzae (NTHi) and its surface plasminogen- (Plg-) binding proteins interact with lipoprotein(a) (Lp(a)) in a lysine-dependent manner.
Zhi Liu +6 more
doaj +1 more source
Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses
Frontiers in Immunology, 2019 Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody–antigen immune ...
M. Tay, K. Wiehe, J. Pollara
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens by polymorphonuclear neutrophil granulocytes, followed by neutrophil apoptosis and removal by macrophages. Neutrophils integrate cues from the
Meriem Sekheri +3 more
semanticscholar +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, EarlyView.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
Phagocytosis Assay of Microglia for Dead Neurons in Primary Rat Brain Cell Cultures
Bio-Protocol, 2016 Clearance of dead brain tissue including the dead neurons through phagocytosis is an endogenous function of microglia in the brain, which is critical for inflammation resolution after ischemic stroke or head trauma.
Xiurong Zhao +3 more
doaj +1 more source
Alzheimer’s Research & Therapy, 2023 Background Hyperhomocysteinemia (HHcy) has been linked to development of Alzheimer’s disease (AD) neuropathologically characterized by the accumulation of amyloid β (Aβ).
Xianwei Wang +13 more
doaj +1 more source
Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. [PDF]
, 2000 Macrophage Fcgamma receptors (FcgammaRs) mediate the uptake and destruction of antibody-coated viruses, bacteria, and parasites. We examined FcgammaR signaling and phagocytic function in bone marrow-derived macrophages from mutant mice lacking the major ...
Crowley, MT +6 more
core
OddzOn Products and Derivation of Invention: At Odds with the Purpose of Section 102(f) of the Patent Act of 1952? [PDF]
, 1999 Background Antimicrobial peptides are important components of the host defence with a broad range of functions including direct antimicrobial activity and modulation of inflammation.
Eugenia Kress +6 more
core +2 more sources