Results 61 to 70 of about 61,316 (277)

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, EarlyView.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Validating Dose Uncertainty Estimates Produced by AUTODIRECT: An Automated Program to Evaluate Deformable Image Registration Accuracy. [PDF]

, 2017
Deformable image registration is a powerful tool for mapping information, such as radiation therapy dose calculations, from one computed tomography image to another. However, deformable image registration is susceptible to mapping errors.
Chen, Josephine, Kim, Hojin, Kirby, Neil, Phillips, Justin, Pukala, Jason, Yom, Sue S   +5 more
core   +3 more sources

Acoustic images of gel dosimetry phantoms

Physics Procedia, 2010
AbstractThis work presents Vibro-acoustography (VA) as a tool to visualize absorbed dose in a polymer gel dosimetry phantom. VA relies on the mechanical excitation introduced by the acoustic radiation force of focused modulated ultrasound in a small region of the object. A hydrophone or microphone is used to measure the sound emitted from the object in
Randall R. Kinnick, Mostafa Fatemi, André L. Baggio, Sílvio Leão Vieira, Antonio Adilton Oliveira Carneiro   +4 more
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Enabling Complex Fibre Geometries Using 3D Printed Axon-Mimetic Phantoms

Frontiers in Neuroscience, 2022
PurposeTo introduce a method to create 3D-printed axon-mimetic phantoms with complex fibre orientations to characterise the performance of diffusion magnetic resonance imaging (MRI) models and representations in the presence of orientation dispersion ...
Tristan K. Kuehn, Tristan K. Kuehn, Farah N. Mushtaha, Ali R. Khan, Ali R. Khan, Ali R. Khan, Ali R. Khan, Ali R. Khan, Corey A. Baron, Corey A. Baron, Corey A. Baron, Corey A. Baron   +11 more
doaj   +1 more source

Design of Anisotropic Diffusion Hardware Fiber Phantoms [PDF]

, 2009
A gold standard for the validation of diffusion weighted magnetic resonance imaging (DW-MRI) in brain white matter (WM) is essential for clinical purposes but still not available.
Baete, Steven, De Deene, Yves, Fieremans, Els, Lemahieu, Ignace   +3 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo [PDF]

, 2020
Significance: Detection and characterization of circulating tumor cells (CTCs), a key determinant of metastasis, are critical for determining risk of disease progression, understanding metastatic pathways, and facilitating early clinical intervention.
Cornelius, Lynn A., Hai, Pengfei, Li, Yang, Qu, Yuan, Shmuylovich, Leonid, Wang, Lihong V., Zhu, Liren   +6 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source