Results 81 to 90 of about 65,250 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Intravascular photoacoustic and optical coherence tomography imaging dual-mode system for detecting spontaneous coronary artery dissection: A feasibility study

Journal of Innovative Optical Health Sciences
In this work, we present an intravascular dual-mode endoscopic system capable of both intravascular photoacoustic imaging (IVPAI) and intravascular optical coherence tomography (IVOCT) for recognizing spontaneous coronary artery dissection (SCAD ...
Yongwei Wang, Yuyang Wan, Zhongjiang Chen   +2 more
doaj   +1 more source

Quantitative imaging: systematic review of perfusion/flow phantoms

European Radiology Experimental, 2020
Background We aimed at reviewing design and realisation of perfusion/flow phantoms for validating quantitative perfusion imaging (PI) applications to encourage best practices.
Marije E. Kamphuis, Marcel J. W. Greuter, Riemer H. J. A. Slart, Cornelis H. Slump   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Advancements in Retinal Tissue-Mimicking Optical Coherence Tomography Phantoms: Materials, Properties, and Applications

BioChem
Optical coherence tomography (OCT) phantoms are essential tools for calibrating imaging systems, validating diagnostic algorithms, and bridging technological advancements with clinical applications. This review explores the development and application of
Mukhit Kulmaganbetov
doaj   +1 more source

Multi-energy computed tomography breast imaging with Monte Carlo simulations: Contrast-to-noise-based image weighting

Journal of Medical Physics, 2019
Context: Photon-counting detectors and breast computed tomography imaging have been an active area of research. With these detectors, photons are assigned an equal weight and weighting schemes can be enabled. More weight can be assigned to lower energies,
Déte Van Eeden, Freek C. P Du Plessis
doaj   +1 more source

ViP MRI: virtual phantom magnetic resonance imaging

Magnetic Resonance Materials in Physics, Biology and Medicine, 2013
The ability to generate reference signals is of great benefit for quantitation of the magnetic resonance (MR) signal. The aim of the present study was to implement a dedicated experimental set-up to generate MR images of virtual phantoms.Virtual phantoms of a given shape and signal intensity were designed and the k-space representation was generated. A
Saint-Jalmes, Hervé, Eliat, Pierre-Antoine, Bezy-Wendling, Johanne, Bordelois, Alejandro, Gambarota, Giulio   +4 more
openaire   +4 more sources

Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination

, 2018
Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique
Darvin, Maxim E., Gersonde, Ingo, Moralejo, Benito, Roth, Martin M., Schleusener, Johannes, Schmälzlin, Elmar, Thiede, Gisela   +6 more
core   +1 more source