Results 101 to 110 of about 1,080,879 (306)
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Microorganisms, 2019 The presence of pharmaceutical products has raised emerging biorisks in aquatic environments. Fungi have been considered in sustainable approaches for the degradation of pharmaceutical compounds from aquatic environments. Soft rot fungi of the Ascomycota
Bo Ram Kang +2 more
doaj +1 more source
Pathways Across the Valley of Death: Novel Intellectual Property Strategies for Accelerated Drug Discovery [PDF]
, 2008 Drug discovery is stagnating. Government agencies, industry analysts, and industry scientists have all noted that, despite significant increases in pharmaceutical R&D funding, the production of fundamentally new drugs - particularly drugs that work on ...
Crossman, Colin +3 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
TOO MUCH DRUG ADVERTISING? A QUALITATIVE PERSPECTIVE OF ROMANIAN PHARMACEUTICAL MARKET [PDF]
Annals of the University of Oradea: Economic Science, 2018 Nowadays, education and health represent key sectors for social and economic progress. Due to the technological and scientific development, drug producers have developed many products.
Ana Valentina Ruse +2 more
doaj
FUZZY MODEL FOR SWOT-ANALYSIS OF PHARMACEUTICAL ENTERPRISE’S FUNCTIONING [PDF]
, 2012 Application of the approach based on fuzzy sets for SWOT-analysis of industrial commercial activity of pharmaceutical enterprises as well as their state and prospects in the competitive market environment have been described.
L. Malyarets, O. Dorokhov
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FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Biochemical Confirmation of Anti-Inflammatory Activity of Oxicam-Based Pharmaceutical Compositions
Journal of the Turkish Chemical Society, Section A: Chemistry, 2018 Biochemical confirmation of anti-inflammatory activity of oxicam-based pharmaceutical compositions was performed by the determination of the level of one of the main markers of inflammation-C-reactive protein.
Ganna Syrova +3 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Antipyretic activity of azima tetracantha in experimental animals [PDF]
, 2011 In the present study, the ethanolic leaf extract of Azima tetracantha Lam (A. tetracantha) was investigated for antipyretic activity in rats using Brewer’s yeast induced Pyrexia. The leaves of A.
Tajuddin Nargis Begum, Mohamed Hussain Muhammad Ilyas, Arumugam Vijaya Anand , Int J Cur Biomed Phar Res.
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