Innovative Approaches to Improving the Process of Risk Management in the Context of Developing a Strategy for the Foreign Economic Activity of Enterprises [PDF]
Marketing i Menedžment InnovacijThe article presents innovative approaches to improving the risk management process in the context of developing a strategy for foreign economic activity of enterprise.
Anzhela Kuznyetsova +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
ON CRIMINAL LIABILITY FOR ADULTERATED MEDICATIONS
Russian Journal of Economics and Law, 2011 Having studied the circulation of adulterrated medications in Russia, the author has stated that in prractice these actions are qualified by the Russian Criminal Code not uniformly, and grounded including into the Russian Crimianal Code of the Artice 238.
Y. Klyushkina
doaj
Searching for Innovations ? The Technological Determinants of Acquisitions in the Pharmaceutical Industry [PDF]
This article analyzes the individual determinants of acquisition activity and target choices in the pharmaceutical industry over the period 1978-2002. The "innovation gap" hypothesis states that acquiring firms lack promising drug compounds and acquire ...
Etienne Pfister, Gautier Duflos
core
Synthesis and study of biological activity of tetrahydro-1H-[3]-benzazepines [PDF]
, 2017 The 3-Benzazepines are an important class of compounds in drug discovery due to their biological activity such as analgesic, antihypertensive or anticancer properties as well as dopaminergic or antidopaminergic activity. In particular, the tetrahydro-1H-[
Díaz, Amelia +4 more
core
Expression of functional recombinant human tissue transglutaminase (TG2) using the bac-to-bac baculovirus expression system [PDF]
, 2016 Purpose: Tissue transglutaminase (TG2) is a unique multifunctional enzyme. The enzyme possesses enzymatic activities such as transamidation/crosslinking and non-enzymatic functions such as cell migration and signal transduction.
Azari, S., Kalhor, H.R., Yazdani, Y.
core +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
FDI spillovers and local productivity growth: evidence from Indian pharmaceutical industry [PDF]
The study tests the FDI spillover hypothesis in the Indian Pharmaceutical industry using an unbalanced panel data for a sample of firms over the period 1989-90 to 2000-01.
Pradhan, Jaya Prakash
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Consolidation and Innovation in the Pharmaceutical Industry: The Role of Mergers and Acquisitions in the Current Innovation Ecosystem [PDF]
, 2018 Recent changes in the pharmaceutical industry have spurred an unprecedented wave of mergers and acquisitions. Some researchers and agencies have questioned whether pharmaceutical consolidation could impede drug innovation.
Shepherd, Joanna
core +2 more sources