Results 51 to 60 of about 374,357 (255)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Pharmaceutical care

open access: yesInpharma Weekly, 1993
A top priority for the American Society of Hospital Pharmacists (ASHP) is the implementation of ‘pharmaceutical care’: a new practice model that will redirect services to focus on patient care rather than products. This was a recurrent theme at the 50th Annual Meeting of the ASHP, held in Denver, US, on June 6th-10th, 1993.
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Implementation of patient prioritisation tools: impact on integrated pharmaceutical care provision

open access: yesInternational Journal of Integrated Care, 2019
Introduction: The Scottish Government’s ambition aims for people to live as long as possible at home or in a homely setting. The projected population increase aged 70+ is 55% by 2035 in [removed] Scottish region.
Pamela Mills, Katie MacLure
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

CONCEPT OF MEDICAL AND PHARMACEUTICAL CARE FOR MYOCARDIAL INFARCTION AS A PROSPECTIVE FORM OF SERVICE TO THE POPULATION

open access: yesМедицина в Кузбассе, 2021
The review is devoted to topical problems of the development of the concept of pharmaceutical care and the interaction of pharmaceutical workers and representatives of medical organizations in the optimization of medical and pharmaceutical care in the ...
Андрей Георгиевич Петров   +3 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Pharmaceutical Care Plus – original scope and significance of pharmaceutical services in primary health care

open access: yesFamily Medicine & Primary Care Review, 2022
JOANNA OBERSKA   +5 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Evaluation of the Community Pharmacy Comorbidities Screening Service on Patients with Chronic Diseases

open access: yesPatient Preference and Adherence, 2021
Jędrzej Lewicki,1 Urszula Religioni,2 Piotr Merks3 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland; 2Collegium of Business Administration, Warsaw School of Economics, Warsaw, Poland ...
Lewicki J, Religioni U, Merks P
doaj  

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