Results 71 to 80 of about 819,937 (301)

An evaluation of antimicrobial stewardship in community pharmacy [PDF]

open access: yes, 2015
This study investigated several aspects of antimicrobial stewardship by gathering information from community pharmacists and members of the public. The aim was to identify how community pharmacists implement antimicrobial stewardship guidelines and ...
Hancock, Laura Jade, Mellor, Callan
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

CONCEPT OF MEDICAL AND PHARMACEUTICAL CARE FOR MYOCARDIAL INFARCTION AS A PROSPECTIVE FORM OF SERVICE TO THE POPULATION

open access: yesМедицина в Кузбассе, 2021
The review is devoted to topical problems of the development of the concept of pharmaceutical care and the interaction of pharmaceutical workers and representatives of medical organizations in the optimization of medical and pharmaceutical care in the ...
Андрей Георгиевич Петров   +3 more
doaj  

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Carmen Peña: apasionadamente boticaria

open access: yesPharmaceutical Care España, 2015
El día 14 Abril de 2015 pasará a la historia de la profesión farmacéutica por dos hechos bien diferentes, pero sin duda con un vínculo muy especial entre ellos.
Merce Martí   +3 more
doaj   +2 more sources

Introducing Pharmaceutical Care to Primary Care in Iceland—An Action Research Study

open access: yesPharmacy, 2017
Even though pharmaceutical care is not a new concept in pharmacy, its introduction and development has proved to be challenging. In Iceland, general practitioners are not familiar with pharmaceutical care and additionally no such service is offered in ...
Anna Bryndis Blondal   +2 more
doaj   +1 more source

Is Taking a Pill a Day Good for Health Expenditures? Evidence from a Cross Section Time Series Analysis of 19 OECD Countries from 1970 – 2000 [PDF]

open access: yes
This paper differs in two ways from previous comparative health system research. First, it focuses on the impact of pharmaceutical expenditures on total health expenditures as trends in pharmaceutical expenditures have been blamed of being a major driver
Verbelen, Bart
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Pharmaceutical Care Plus – original scope and significance of pharmaceutical services in primary health care

open access: yesFamily Medicine & Primary Care Review, 2022
JOANNA OBERSKA   +5 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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