Results 151 to 160 of about 3,535,062 (289)

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

A Technical Framework for Predicting Regulatory Deficiencies in Pharmaceutical Chemistry, Manufacturing, and Controls (CMC) Submissions Using Machine Learning. [PDF]

Cureus
Modi P.
europepmc   +1 more source

Reactivity‐Guided Janus Graphene With Asymmetric Interfacial Electrostatics for Tunable Charge Transport

Advanced Materials, EarlyView.
Stepwise dual‐side functionalization creates covalent Janus graphene with chemically and electrostatically asymmetric interfaces. The resulting nonadditive surface‐potential response and pronounced charge‐transport modulation demonstrate a versatile route for tailoring the electronic properties of graphene.
Shishi Liu, Zhuting Hao, Mira Kreßler, Oguzhan Yücel, Lotte Polling, Adrián Dewambrechies, Wesley Pietsch, Philip Nickl, Felix Fels, Kevin Pagel, Markus R. Heinrich, Patryk Kusch, Kirill Bolotin, Xin Chen, Siegfried Eigler   +14 more
wiley   +1 more source

Methanesulfonic Acid as a Dual‐Role Reagent for Porous Polymer Network Design

Advanced Materials, EarlyView.
The design of porous polymer networks (PPNs) using methanesulfonic acid (MSA) as a dual‐role reagent facilitates the synthesis of robust PPNs for specific applications. It also makes the scale‐up process techno‐economically feasible because MSA functions simultaneously as both a solvent and a catalyst for the reaction.
Kelechi Festus, Arnab Ghosh, Ankit Mondal, Theresa Ariri, Suman Mandal, Ahana Sarkar, Urme Podder, Qingsheng Wang, Hong‐Cai Zhou   +8 more
wiley   +1 more source

Correction "<i>ACS Bio & Med Chem Au</i>: Introducing the 2024 Rising Stars in Biological, Medicinal, and Pharmaceutical Chemistry". [PDF]

ACS Bio Med Chem Au
Booker SJ.
europepmc   +1 more source

Pulsed Oxidative–Reductive Electrolysis Over Dual Cu and Co Single‐Atom Sites for Urea Electrosynthesis

Advanced Materials, EarlyView.
Alternating oxidative–reductive pulses synchronize CO2‐derived *CO and NH3‐derived *NHx intermediates over dual Cu and Co single‐atom sites, enabling urea and ethyl urea formation with a total C─N Faradaic efficiency of 42 ± 4%. In situ spectroscopy and theoretical calculations elucidate complementary Cu and Co functions, while oxidative controls ...
Putri Ramadhany, Peiqi Qiu, Thành Trần‐Phú, Denny Gunawan, Bernt Johannessen, Rosalie K. Hocking, Yan Jiao, Rose Amal, Rahman Daiyan   +8 more
wiley   +1 more source

Chemistry

, 2013
Chemistry Department Self Study Report for Academic Program ReviewChemistry Department Self Study Report Academic Program ReviewChemistry Department Self Study Report Academic Program ...
Chemistry Department, Chemistry, Self Study Report, Academic Program Review, APR   +2 more
core  

Kirigami‐Inspired Stretchable Silicon Solar Cell Modules as Portable Power Sources

Advanced Materials, EarlyView.
Kirigami‐inspired structured substrates are designed to craft stretchable silicon solar cell modules, showcasing remarkable stability upon deformation and retaining high output efficiency. This innovative approach holds great promise for the utilization of silicon modules for wearable devices.
Yusheng Zhang, Chenyi Zhang, Pei Wang, Yetai Cheng, Qi Liang, Yonghuan Li, Zhengdong Wei, Huanyu Zhou, Xinyi Kong, Minghua Li, Yifan Wang, Zhishan Bo, Yuqiang Liu, Antonio Facchetti   +13 more
wiley   +1 more source

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

Advanced Materials Interfaces, EarlyView.
Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi, Aniruddh Murali, Ellen Juel Pørtner, Adam Cohen Simonsen, Francesca Serra   +4 more
wiley   +1 more source