Results 11 to 20 of about 1,650,445 (352)

A novel approach to the application of hexagonal mesoporous silica in solid-phase extraction of drugs

Heliyon, 2018
Mesoporous silica with hexagonal type structure containing amine functional group was introduced. Firstly, aminopropyl hexagonal mesoporous silica was synthetized in a co-condensation process, via templating route of n-dodecylamine.
Fatemeh Farjadian, Soha Azadi, Soliman Mohammadi-Samani, Hajar Ashrafi, Amir Azadi   +4 more
doaj   +1 more source

Synthesis and synergistic studies of isatin based mixed ligand complexes as potential antifungal therapeutic agents

Heliyon, 2019
Metal based drugs are important class of chemotherapeutic agents that have the potential to circumvent drug resistance. Increasing drug resistance, treatment failures and limited treatment options necessitates the development of new therapeutic drugs ...
Ovas Ahmad Dar, Shabir Ahmad Lone, Manzoor Ahmad Malik, Faisal Mohammed Aqlan, Mohmmad Younus Wani, Athar Adil Hashmi, Aijaz Ahmad   +6 more
doaj   +1 more source

Isolation and identification of phenolic antioxidants from Pistacia integerrima gall and their anticholine esterase activities

Heliyon, 2018
The galls of Pistacia integerrima are utilized in folk medicines for the treatment of cough, asthma, dysentery, liver disorders and for snake bite. A number of biological active compounds like alkaloids, flavonoids, tannins, saponins and sterols from ...
Muhammad Zahoor, Roheena Zafar, Naveed Ur Rahman   +2 more
doaj   +1 more source

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

Heliyon, 2019
A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy.
Chandrabose Karthikeyan, Haneen Amawi, Charles R. Ashby, Jr., Vishwa M. Khare, Veronica Jones, N.S. Hari Narayana Moorthy, Piyush Trivedi, Amit K. Tiwari   +7 more
doaj   +1 more source

Incorporating Stories of Sedatives, Spoiled Sweet Clover Hay, and Plants from the Amazon Rainforest into a Pharmaceutical Chemistry Course To Engage Students and Introduce Drug Design Strategies

Journal of Chemical Education, 2018
This article describes three historical cases of drug discovery and how they were adapted as examples to teach chemical analysis to students pursuing a pharmacy (UK MPharm) and pharmaceutical sciences (BSc Pharmaceutical Sciences) degree.
E. Larrañeta
semanticscholar   +1 more source

Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands

Heliyon, 2019
Organic molecule dithiocarbamate transition metal complexes are novel and very attractive pharmaceutical targets for the management and control of antibiotic resistant bacteria. The direct reaction has synthesized new transition metal nickel (II), copper
Senthilkumar Balakrishnan, Senbagam Duraisamy, Murugan Kasi, Selvam Kandasamy, Rajesh Sarkar, Anbarasu Kumarasamy   +5 more
doaj   +1 more source

Silver nanoparticle synthesis by Acalypha wilkesiana extract: phytochemical screening, characterization, influence of operational parameters, and preliminary antibacterial testing

Heliyon, 2019
Single pot green synthesis of silver nanoparticles (AgNPs) was successfully carried out using medicinal plant extract of Acalypha wilkesiana via bottom-up approach. Five imperative operational parameters (pH, contact time, concentration, volume ratio and
Adewumi Oluwasogo Dada, Folahan Amoo Adekola, Fehintoluwa Elizabeth Dada, Adunola Tabitha Adelani-Akande, Micheal Oluwasesan Bello, Chidiogo Rita Okonkwo, Adejumoke Abosede Inyinbor, Abimbola Peter Oluyori, Adeniyi Olayanju, Kolawole Oluseyi Ajanaku, Charles Oluwaseun Adetunji   +10 more
doaj   +1 more source

29th Annual GP2A Medicinal Chemistry Conference

Pharmaceuticals, 2021
The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021.
Jean-Jacques Helesbeux, Laura Carro, Florence O. McCarthy, Vânia M. Moreira, Francesca Giuntini, Niamh O’Boyle, Susan E. Matthews, Gülşah Bayraktar, Samuel Bertrand, Christophe Rochais, Pascal Marchand   +10 more
doaj   +1 more source

Design, synthesis, biological evaluation and molecular docking studies of novel 3-substituted-5-[(indol-3-yl)methylene]-thiazolidine-2,4-dione derivatives

Heliyon, 2018
Various thiazolidine-2,4-dione derivatives 3a-l possessing indole moiety were designed, synthesized using appropriate conventional heating as well as microwave irradiation methods.
K. Srikanth Kumar, A. Lakshmana Rao, M.V. Basaveswara Rao   +2 more
doaj   +1 more source

Broadening the Perspective on Reducing Pharmaceutical Residues in the Environment

Environmental Toxicology and Chemistry, 2023
The present study reviews options for reducing harm from pharmaceuticals that are known to cause adverse impacts by their presence in the environment. It reviews recent global and European Union policy development, which could go further in recognizing ...
K. Helwig, L. Niemi, J-Y Stenuick, J. Alejandre, S. Pfleger, J. Roberts, J. Harrower, I. Nafo, O. Pahl   +8 more
semanticscholar   +1 more source