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Mass transport of pharmaceutical cocrystals
2018<p>Cocrystals have two or more neutral components (drug and cocrystal former) in the same crystal lattice which are held together via non-covalent bonds. Since the presence of the cocrystal former alters the energy of the drug molecules and their physicochemical properties, the drug dissolution characteristics can be manipulated by ...
Hui Zu +6 more
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Pharmaceutical Cocrystals: Molecules, Crystals, Formulations, Medicines
Crystal Growth & Design, 2019Cocrystals are long known yet recently applied molecular entities. In the past decade, a significant potential has been demonstrated by these novel solids in terms of modifying the physicochemical ...
Malaz A. E. Yousef, Venu R. Vangala
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Pharmaceutical Cocrystal and Salts of Norfloxacin
Crystal Growth & Design, 2006The aim of this study was to investigate the structural and pharmaceutical properties of norfloxacin (a poorly soluble antibacterial drug), its cocrystal, and salts. Norfloxacin in the anhydrous form (form A, 1) was crystallized. It was cocrystallized with isonicotinamide (2), and organic salts were prepared with succinic acid, malonic acid, and maleic
Srinivas Basavoju +2 more
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Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques
Advanced Drug Delivery Reviews, 2017The main goal of a novel drug development is to obtain it with optimal physiochemical, pharmaceutical and biological properties. Pharmaceutical companies and scientists modify active pharmaceutical ingredients (APIs), which often are cocrystals, salts or carefully selected polymorphs, to improve the properties of a parent drug. To find the best form of
Edyta, Pindelska +2 more
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Solution Stability of Pharmaceutical Cocrystals
Crystal Growth & Design, 2022Amin Alvani, Ali Shayanfar
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Cocrystal Systems of Pharmaceutical Interest: 2007–2008
2010Publisher Summary The chapter focuses on the literature published primarily during 2007 and 2008 regarding cocrystal systems that have a pharmaceutical interest. The literature cited in the chapter reviews primarily from the major physical, crystallographic, and pharmaceutical journals, and consequently the coverage cannot be represented as being ...
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Cocrystal Systems of Pharmaceutical Interest: 2012–2014
2019Developments in the field of pharmaceutical cocrystals have been documented in the form of chronological review articles, and the present review encompasses articles published during 2012, 2013, and 2014. Appropriate publications were drawn from the major physical, crystallographic, and pharmaceutical journals, being sorted according to the identity of
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Crystal Engineering of Pharmaceutical Cocrystals
2013In the last years, the design and synthesis of co-crystals containing active pharmaceutical ingredients (APIs) has become the new frontier of the crystal engineering due to the great opportunity to modify the physico-chemical properties of solid forms of drugs.
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Pharmaceutical Cocrystal Formation Using Lipid Media
Journal of the Society of Powder Technology, Japan, 2023Yusuke Shimoyama, Yuna Tatsumi
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