Results 101 to 110 of about 537,841 (319)

Why licensing authorities need to consider the net value of new drugs in assigning review priorities: Addressing the tension between licensing and reimbursement [PDF]

open access: yes, 2008
Pharmaceutical regulators and healthcare reimbursement authorities operate in different intellectual paradigms and adopt very different decision rules. As a result, drugs that have been licensed are often not available to all patients who could benefit ...
Angell   +6 more
core   +1 more source

Risk management for analytical methods: conciliating objectives of methods, validation phase and routine decision rules [PDF]

open access: yesDans Actes du congr\`es de Chimiom\'etrie 2005 - Risk management for analytical methods: conciliating objectives of methods, validation phase and routine decision rules., France (2005), 2007
In the industries that involved either chemistry or biology, such as pharmaceutical industries, chemical industries or food industry, the analytical methods are the necessary eyes and hear of all the material produced or used. If the quality of an analytical method is doubtful, then the whole set of decision that will be based on those measures is ...
arxiv  

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

The Global Pharmaceutical Industry, 2004 [PDF]

open access: yes
This teaching case looks at the development of the ethical pharmaceutical industry. The various forces affecting the discovery, development, production, distribution and marketing of prescription drugs are discussed in terms of their origins and recent ...
Bernardo Batiz-Lazo, k Sarah Holland
core  

Reform progress and achievements of China’s incentive policies for pediatric medicine over the last decade

open access: yesFrontiers in Pharmacology
BackgroundThe accessibility of pediatric medicine is a global challenge. The issuance of the “Several Opinions on Ensuring the Use of Children’s Medicine” by six ministries in China in 2014 marked the formation of the policy framework. This study aims to
Qiwei Wang   +8 more
doaj   +1 more source

Stable Radical Polymers as New Electroactive Materials: Synthesis, Properties, and Emerging Applications

open access: yesAdvanced Functional Materials, EarlyView.
This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong   +11 more
wiley   +1 more source

Sustained Release of Proteins Using Region‐Specific Tunable Degradability in Hydrogels through 3D Photopatterning and Complimentary Labile Bond Chemistry

open access: yesAdvanced Functional Materials, EarlyView.
A series of ultraviolet‐ and near‐infrared radiation sensitive photoactivatable hydrogels are developed that can be controlled spatiotemporally down to µm precisions using one‐ and two‐photon uncaging. The latent hydroxylamine‐, hydrazine‐, and amine uncaged moieties are used to photopattern a series of diverse proteins displaying complimentary ...
Tove Kivijärvi   +6 more
wiley   +1 more source

IMPLEMENTATION MECHANISMS OF INNOVATIVE STRATEGIES IN PHARMACEUTICAL INDUSTRY AND KEY INVESTMENT PROJECTS

open access: yesСтатистика и экономика, 2016
In this article, the author reflects the strategic goals, principles and objectives of the pharmaceutical industry, the situation in the industry, the industry's problems, methods and ways of solving these problems.
Marko Jovanovich
doaj   +1 more source

Revolutionizing Pharma: Unveiling the AI and LLM Trends in the Pharmaceutical Industry [PDF]

open access: yesarXiv
This document offers a critical overview of the emerging trends and significant advancements in artificial intelligence (AI) within the pharmaceutical industry. Detailing its application across key operational areas, including research and development, animal testing, clinical trials, hospital clinical stages, production, regulatory affairs, quality ...
arxiv  

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

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