Results 101 to 110 of about 4,080,009 (401)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano +39 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Pharmaceutical M&A Activity: Effects on Prices, Innovation, and Competition [PDF]
, 2017 The rise of blockbuster pharmaceutical acquisitions has prompted fears that unprecedented market concentration will weaken competition. Two of the most prominent concerns focus on the upstream and downstream ends of the pharmaceutical industry: (1) the ...
Mitchell, Will +3 more
core +1 more source
Blockchain Technology in Pharmaceutical Industry to Prevent Counterfeit Drugs
, 2018 The production and distribution of counterfeit drugs is an urgent and increasingly critical worldwide issue, especially in developing countries. The market value of pharmaceutical counterfeiting has reached billions of dollars annually.
Ijazul Haq, Olivier Muselemu
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
La industria farmacéutica granadina durante el franquismo (19361975)
Ars PharmaceuticaResumen Objetivo: Estudiamos los laboratorios farmacêuticos que estuvieron en funcionamiento en la provincia de Granada durante el franquismo (1936-1975), tanto los creados con anterioridad a la guerra civil, como los establecidos durante este conflicto
Antonio Bueno González +1 more
doaj +1 more source
Scale-up of electrospinning technology: Applications in the pharmaceutical industry.
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2019 Recently, electrospinning (ES) of fibers has been shown to be an attractive strategy for drug delivery. One of the main features of ES is that a wide variety of drugs can be loaded into the fibers to improve their bioavailability, to enhance dissolution,
Panna Vass +11 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Does Public Scientific Research Complement Industry R&D Investment? The Case of NIH Supported Basic and Clinical Research and Pharmaceutical Industry R&D [PDF]
This research investigates the hypothesis that publicly funded scientific research complements private R&D investment in the pharmaceutical industry. New microlevel data on public research investment by the U.S.
Toole, Andrew A.
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