Results 21 to 30 of about 537,841 (319)
Evidence suggested that the use of partial dopamine D2/D3 receptor agonists may be a better choice for the treatment of Parkinson's disease (PD), and the stimulation of 5-HT1A receptors (mainly via nondopaminergic mechanisms) alleviates motor and ...
Xin-Li Du+7 more
doaj +1 more source
Bifidobacteria are considered one of the most important intestinal probiotics because of their significant health impact. However, this ability is usually limited by gastrointestinal fluid and temperature sensitivity. Emulsification and internal gelation
Rui Ji+13 more
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Pharmacovigilance in the pharmaceutical industry [PDF]
Pharmacovigilance has been defined as the process of identifying and responding to drug safety issues [1] and has grown considerably as a discipline over the past 10 to 15 years. An educational survey in 1994 revealed that more than 320 people currently worked in company pharmacovigilance functions in the UK alone [2].
J. C. C. Talbot, B. S. Nilsson
openaire +3 more sources
The implications of WTO accession on the pharmaceutical industry in China [PDF]
Given the limited capabilities of R&D and global distribution channels, and the virtual non-existence of patented drugs, the Chinese pharmaceutical industry has little chance to enter the global market of Western prescription drugs and compete with the ...
Yeung, Godfrey
core +1 more source
Twelve impurities (process-related and degradation) in lisdexamfetamine dimesylate (LDX), a central nervous system (CNS) stimulant drug, were first separated and quantified by high-performance liquid chromatography (HPLC) and then identified by liquid ...
Shenghua Gao+5 more
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In this study, the synthesis and biological evaluation of a variety of benzoheterocyclic-containing benzamide derivatives were described. Some of these compounds were proved to inhibiting the activity of histone deacetylase 1 (HDAC1) with IC50 values ...
Min-Ru Jiao+5 more
doaj +1 more source
Industry-scale application and evaluation of deep learning for drug target prediction [PDF]
Artificial intelligence (AI) is undergoing a revolution thanks to the breakthroughs of machine learning algorithms in computer vision, speech recognition, natural language processing and generative modelling.
Ashby, Thomas J.+18 more
core +1 more source
Assessment of the Utilization of Quadruped Robots in Pharmaceutical Research and Development Laboratories [PDF]
Drug development is becoming more and more complex and resource-intensive. To reduce the costs and the time-to-market, the pharmaceutical industry employs cutting-edge automation solutions. Supportive robotics technologies, such as stationary and mobile manipulators, exist in various laboratory settings.
arxiv +1 more source
Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin
Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes.
Yiwen Huang+3 more
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Pharmaceutical industry before COVID-19 [PDF]
The 2019 CPhI Annual Report describing rankings, innovations and key trends in pharma industry is summarized. Pharmaceutical markets were assessed based on an the following indicators: growth potential, API manufacturing, innovation, competitiveness and ...
Krzysztof Woyna-Orlewicz+1 more
doaj +1 more source