Results 21 to 30 of about 574,105 (363)
Evidence suggested that the use of partial dopamine D2/D3 receptor agonists may be a better choice for the treatment of Parkinson's disease (PD), and the stimulation of 5-HT1A receptors (mainly via nondopaminergic mechanisms) alleviates motor and ...
Xin-Li Du +7 more
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Pharmaceutical industry before COVID-19 [PDF]
The 2019 CPhI Annual Report describing rankings, innovations and key trends in pharma industry is summarized. Pharmaceutical markets were assessed based on an the following indicators: growth potential, API manufacturing, innovation, competitiveness and ...
Krzysztof Woyna-Orlewicz +1 more
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Bifidobacteria are considered one of the most important intestinal probiotics because of their significant health impact. However, this ability is usually limited by gastrointestinal fluid and temperature sensitivity. Emulsification and internal gelation
Rui Ji +13 more
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In this study, the synthesis and biological evaluation of a variety of benzoheterocyclic-containing benzamide derivatives were described. Some of these compounds were proved to inhibiting the activity of histone deacetylase 1 (HDAC1) with IC50 values ...
Min-Ru Jiao +5 more
doaj +1 more source
A cross-sectional analysis of pharmaceutical industry-funded events for health professionals in Australia [PDF]
Objectives: To analyse patterns and characteristics of pharmaceutical industry sponsorship of events for Australian health professionals and to understand the implications of recent changes in transparency provisions that no longer require reporting of ...
Bero, Lisa A +6 more
core +1 more source
Twelve impurities (process-related and degradation) in lisdexamfetamine dimesylate (LDX), a central nervous system (CNS) stimulant drug, were first separated and quantified by high-performance liquid chromatography (HPLC) and then identified by liquid ...
Shenghua Gao +5 more
doaj +1 more source
Regulating the pharmaceutical industry [PDF]
The pharmaceutical price regulation scheme1 is a voluntary agreement between Britain's Department of Health and the Association of the British Pharmaceutical Industry in which companies negotiate generous target profit rates from sales of drugs to the NHS (17-21% rate of return on investment in research and development).
A, Maynard, K, Bloor
openaire +2 more sources
Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin
Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes.
Yiwen Huang +3 more
doaj +1 more source
Innovation in the pharmaceutical industry [PDF]
The pharmaceutical industry today is operating in an environment whose main feature is an unprecedented pace of change. In most markets the rising costs of health care are of increasing concern, and the medicines bill is being targeted for savings. New constraints are limiting the medicines that can be used and paid for in the system.
openaire +2 more sources
Biomarkers in the Pharmaceutical Industry [PDF]
Although biomarkers have been the essence of laboratory medicine since its inception, they are relatively new tools in the development of pharmaceutical compounds. The main utility of biomarkers for pharmaceutical companies has been in making drug development a more efficient and a cost-effective process.
Omar F, Laterza +6 more
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