Results 21 to 30 of about 574,105 (363)

Synthesis and Biological Evaluation of a Series of Novel 1-(3-((6-Fluoropyridin-3-yl)oxy)propyl)piperazines as Dopamine/Serotonin Receptor Agonists

open access: yesPharmaceutical Fronts, 2022
Evidence suggested that the use of partial dopamine D2/D3 receptor agonists may be a better choice for the treatment of Parkinson's disease (PD), and the stimulation of 5-HT1A receptors (mainly via nondopaminergic mechanisms) alleviates motor and ...
Xin-Li Du   +7 more
doaj   +1 more source

Pharmaceutical industry before COVID-19 [PDF]

open access: yesFarmacja Polska, 2020
The 2019 CPhI Annual Report describing rankings, innovations and key trends in pharma industry is summarized. Pharmaceutical markets were assessed based on an the following indicators: growth potential, API manufacturing, innovation, competitiveness and ...
Krzysztof Woyna-Orlewicz   +1 more
doaj   +1 more source

Extending Viability of Bifidobacterium longum in Chitosan-Coated Alginate Microcapsules Using Emulsification and Internal Gelation Encapsulation Technology

open access: yesFrontiers in Microbiology, 2019
Bifidobacteria are considered one of the most important intestinal probiotics because of their significant health impact. However, this ability is usually limited by gastrointestinal fluid and temperature sensitivity. Emulsification and internal gelation
Rui Ji   +13 more
doaj   +1 more source

Design, Synthesis, and Evaluation of Benzoheterocyclic-Containing Derivatives as Novel HDAC1 Inhibitors

open access: yesPharmaceutical Fronts, 2022
In this study, the synthesis and biological evaluation of a variety of benzoheterocyclic-containing benzamide derivatives were described. Some of these compounds were proved to inhibiting the activity of histone deacetylase 1 (HDAC1) with IC50 values ...
Min-Ru Jiao   +5 more
doaj   +1 more source

A cross-sectional analysis of pharmaceutical industry-funded events for health professionals in Australia [PDF]

open access: yes, 2017
Objectives: To analyse patterns and characteristics of pharmaceutical industry sponsorship of events for Australian health professionals and to understand the implications of recent changes in transparency provisions that no longer require reporting of ...
Bero, Lisa A   +6 more
core   +1 more source

Identification, Characterization and Quantification of Process-Related and Degradation Impurities in Lisdexamfetamine Dimesylate: Identifiction of Two New Compounds

open access: yesMolecules, 2018
Twelve impurities (process-related and degradation) in lisdexamfetamine dimesylate (LDX), a central nervous system (CNS) stimulant drug, were first separated and quantified by high-performance liquid chromatography (HPLC) and then identified by liquid ...
Shenghua Gao   +5 more
doaj   +1 more source

Regulating the pharmaceutical industry [PDF]

open access: yesBMJ, 1997
The pharmaceutical price regulation scheme1 is a voluntary agreement between Britain's Department of Health and the Association of the British Pharmaceutical Industry in which companies negotiate generous target profit rates from sales of drugs to the NHS (17-21% rate of return on investment in research and development).
A, Maynard, K, Bloor
openaire   +2 more sources

Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin

open access: yesMolecules, 2016
Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes.
Yiwen Huang   +3 more
doaj   +1 more source

Innovation in the pharmaceutical industry [PDF]

open access: yesBMJ, 1994
The pharmaceutical industry today is operating in an environment whose main feature is an unprecedented pace of change. In most markets the rising costs of health care are of increasing concern, and the medicines bill is being targeted for savings. New constraints are limiting the medicines that can be used and paid for in the system.
openaire   +2 more sources

Biomarkers in the Pharmaceutical Industry [PDF]

open access: yesClinical Chemistry, 2015
Although biomarkers have been the essence of laboratory medicine since its inception, they are relatively new tools in the development of pharmaceutical compounds. The main utility of biomarkers for pharmaceutical companies has been in making drug development a more efficient and a cost-effective process.
Omar F, Laterza   +6 more
openaire   +2 more sources

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