Results 31 to 40 of about 574,105 (363)

Improvement of Nemadectin Production by Overexpressing the Regulatory Gene nemR and Nemadectin Biosynthetic Gene Cluster in Streptomyces Cyaneogriseus

Pharmaceutical Fronts, 2020
Nemadectin, a 16-member macrocyclic lactone antiparasitic antibiotic, is produced by Streptomyces cyaneogriseus subspecies noncyanogenus. Moxidectin, a C-23 oximate derivative of nemadectin, is widely used as a pesticide due to its broad-spectrum, highly
Yuan-Jie Wu, Song-Bai Yang, Zheng-Yu Zhang, Shao-Xin Chen   +3 more
doaj   +1 more source

Processing-Induced Disorder in Pharmaceutical Materials [PDF]

, 2016
This chapter focuses on the major types of pharmaceutical processing methods that have been widely reported to produce disordered material either intentionally or unintentionally.
Al-Obaidi, Alkhatib, Alonzo, Bahl, Balani, Breitenbach, Brough, Brown, Cal, Cerea, Chakraborty, Chattoraj, Chieng, Clark, Cordeiro, Cui, De Beer, Descamps, DiNunzio, Dinunzio, El-Badry, Elamin, Felton, Feng, Forster, Gazzaniga, Graeser, Guns, Gupta, He, Hu, Hu, Janssens, Kang, Karmwar, Ke, Keen, Khan, Kim, Koivisto, Lai, Laitinen, Laitinen, Lang, Lauer, Luisi, Luo, Löbmann, Löbmann, Nagy, Ng, Norrman, Otte, Otte, Passerini, Patterson, Porter, Qi, Qi, Qi, Qi, Repka, Riippi, Saerens, Sammoura, Santivarangkna, Sauer, Sauer, Sill, Sollohub, Tang, Trasi, Trasi, Van den Brande, Van Eerdenbrugh, Van Eerdenbrughand, Van Melkebeke, Vehring, Weatherley, Weuts, Willart, Willart, Willart, Williams, Windbergs, Windbergs, Wojnarowska, Yang, Zamani, Zema   +89 more
core   +1 more source

Medicine and the pharmaceutical industry [PDF]

Developmental Medicine & Child Neurology, 2006
One privilege of working in the health service today is the enormous range of effective therapies available to us. Advances in surgical techniques, tools, and materials have been more than matched by the vast number of pharmaceutical products addressing an ever wider range of conditions. Even for conditions where treatments have been available for many
openaire   +2 more sources

An Overview of Progress in the International Regulation of the Pharmaceutical Industry [PDF]

, 2002
[Excerpt] “The pharmaceutical industry, a significant source of healthcare throughout the world, has several features that distinguish it from the rest of the health industry.
Burakoff, Aaron, Harvard University, Costa-Font, Joan   +1 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Development of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine

Scientific Reports
In Traditional Chinese Medicine (TCM), the medicinal leech is vital for treatments to promote blood circulation and eliminate blood stasis. However, the prevalence of counterfeit leech products in the market undermines the quality and efficacy of these ...
Chenfeng Shi, Yuhan Guo, Lijuan Yao, Yunhui Xu, Jing Zhou, Moli Hua   +5 more
doaj   +1 more source

Transformers: African American Women Leaders in the Pharmaceutical Industry [PDF]

, 2016
This qualitative study documents the experiences of African American women leaders in the pharmaceutical industry in the context of the transformative leadership model. Transformative leadership is a theory that recognizes that the success of individuals
Bonaparte, Yvette Lynne
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Pharmaceutical Industry\u27s Effect on Socioeconomic Development in Sub-Saharan Africa in Relation to Family Planning Accessibility [PDF]

, 2019
There is a large unmet need for family planning services in sub-Saharan Africa (Goodkind et al, 2018). Pharmaceutical companies contribute to the accessibility of medications in developing countries (Cottingham & Berer, 2011).
Demarest, Tessa
core   +1 more source

Making regulation responsive to commercial interests: streamlining drug industry watchdogs [PDF]

, 2002
New prescription drugs are developed and tested for quality, safety, and efficacy by the pharmaceutical industry, and little or no drug testing is conducted by governments in modern industrialised countries.
Abraham, John
core   +2 more sources