Results 41 to 50 of about 4,080,009 (401)

Extending Viability of Bifidobacterium longum in Chitosan-Coated Alginate Microcapsules Using Emulsification and Internal Gelation Encapsulation Technology

open access: yesFrontiers in Microbiology, 2019
Bifidobacteria are considered one of the most important intestinal probiotics because of their significant health impact. However, this ability is usually limited by gastrointestinal fluid and temperature sensitivity. Emulsification and internal gelation
Rui Ji   +13 more
doaj   +1 more source

Synthesis and Biological Evaluation of a Series of Novel 1-(3-((6-Fluoropyridin-3-yl)oxy)propyl)piperazines as Dopamine/Serotonin Receptor Agonists

open access: yesPharmaceutical Fronts, 2022
Evidence suggested that the use of partial dopamine D2/D3 receptor agonists may be a better choice for the treatment of Parkinson's disease (PD), and the stimulation of 5-HT1A receptors (mainly via nondopaminergic mechanisms) alleviates motor and ...
Xin-Li Du   +7 more
doaj   +1 more source

Are Financial Payments From the Pharmaceutical Industry Associated With Physician Prescribing?

open access: yesAnnals of Internal Medicine, 2020
BACKGROUND Financial payments from the drug industry to U.S. physicians are common. Payments may influence physicians' clinical decision making and drug prescribing.
Aaron P. Mitchell   +7 more
semanticscholar   +1 more source

Identification, Characterization and Quantification of Process-Related and Degradation Impurities in Lisdexamfetamine Dimesylate: Identifiction of Two New Compounds

open access: yesMolecules, 2018
Twelve impurities (process-related and degradation) in lisdexamfetamine dimesylate (LDX), a central nervous system (CNS) stimulant drug, were first separated and quantified by high-performance liquid chromatography (HPLC) and then identified by liquid ...
Shenghua Gao   +5 more
doaj   +1 more source

Design, Synthesis, and Evaluation of Benzoheterocyclic-Containing Derivatives as Novel HDAC1 Inhibitors

open access: yesPharmaceutical Fronts, 2022
In this study, the synthesis and biological evaluation of a variety of benzoheterocyclic-containing benzamide derivatives were described. Some of these compounds were proved to inhibiting the activity of histone deacetylase 1 (HDAC1) with IC50 values ...
Min-Ru Jiao   +5 more
doaj   +1 more source

A cross-sectional analysis of pharmaceutical industry-funded events for health professionals in Australia [PDF]

open access: yes, 2017
Objectives: To analyse patterns and characteristics of pharmaceutical industry sponsorship of events for Australian health professionals and to understand the implications of recent changes in transparency provisions that no longer require reporting of ...
Bero, Lisa A   +6 more
core   +1 more source

Pharmacovigilance in the pharmaceutical industry [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1998
Pharmacovigilance has been defined as the process of identifying and responding to drug safety issues [1] and has grown considerably as a discipline over the past 10 to 15 years. An educational survey in 1994 revealed that more than 320 people currently worked in company pharmacovigilance functions in the UK alone [2].
J. C. C. Talbot, B. S. Nilsson
openaire   +3 more sources

Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin

open access: yesMolecules, 2016
Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes.
Yiwen Huang   +3 more
doaj   +1 more source

A Detailed Case Study on Deviation, Out-of-Specification(OOS) and CAPA Generation in Pharmaceutical Industry

open access: yesInternational Journal of Innovative Science and Research Technology
This review provide an overview of the various documentation of quality management system, which includes deviations, OOS and CAPA. A detailed case study of deviations, out-of-Specification and CAPA generation is beneficial for improving pharmaceutical ...
Arefa Khan   +3 more
semanticscholar   +1 more source

Improvement of Nemadectin Production by Overexpressing the Regulatory Gene nemR and Nemadectin Biosynthetic Gene Cluster in Streptomyces Cyaneogriseus

open access: yesPharmaceutical Fronts, 2020
Nemadectin, a 16-member macrocyclic lactone antiparasitic antibiotic, is produced by Streptomyces cyaneogriseus subspecies noncyanogenus. Moxidectin, a C-23 oximate derivative of nemadectin, is widely used as a pesticide due to its broad-spectrum, highly
Yuan-Jie Wu   +3 more
doaj   +1 more source

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