Results 61 to 70 of about 258,478 (322)

Primary pharmaceutical manufacturing scheduling problem [PDF]

open access: yesIIE Transactions, 2014
This article addresses an integrated lot-sizing and scheduling problem that arises in the primary manufacturing phase of a pharmaceutical supply chain. Multiple pharmaceutical ingredients and their intermediate products are to be scheduled on parallel and capacitated bays for production in batches.
Hanif D. Sherali   +2 more
openaire   +2 more sources

Pengaruh Struktur Modal Terhadap Profitabilitas Pada Perusahaan Manufaktur Sektor Farmasi Yang Terdaftar Di Bursa Efek Indonesia [PDF]

open access: yes, 2017
The study aims to determine the effect of capital structure on profitability in the pharmaceutical sector manufacturing companies listed on the Indonesian stock exchange.
Ibrahim, M. (Mariaty)   +1 more
core  

Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]

open access: yes, 2018
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B.   +3 more
core   +2 more sources

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

A unique collaboration to promote sustainability for pharmaceuticals and fine chemicals: the GSK-Singapore Partnership for Green and Sustainable Manufacturing

open access: yesGreen Processing and Synthesis, 2012
The GSK-Singapore Partnership for Green and Sustainable Manufacturing is a public-private partnership with the objectives of: Enhancing Singapore’s capabilities to address the sustainable manufacturing challenges experienced by the pharmaceutical ...
Dell’Orco Philip   +3 more
doaj   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Upstream pharmaceutical supply chains of 10 high-use pharmaceuticals in the Netherlands: a cohort study

open access: yesBMJ Open
Objectives To assess the upstream pharmaceutical supply chains of 10 high-use pharmaceuticals to detect vulnerabilities that may increase the risk of medicine shortages.Design Cohort study.Setting Dutch outpatient setting in 2022.Participants A total of ...
Aukje K Mantel-Teeuwisse   +4 more
doaj   +1 more source

The other GMP: good manufacturing practice and its importance in the validation of constructed pharmaceutical facilities [PDF]

open access: yes, 2005
The work reported is part of an ongoing PhD study prompted by the particular difficulties encountered when two very different quality cultures interact (in this case Pharmaceutical industry clients and Construction industry providers).
Edge, Jerry   +2 more
core  

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