Results 81 to 90 of about 2,713,900 (282)

Recurrent Neural Network-based Model Predictive Control for Continuous Pharmaceutical Manufacturing [PDF]

open access: yesMathematics, 2018
The pharmaceutical industry has witnessed exponential growth in transforming operations towards continuous manufacturing to increase profitability, reduce waste and extend product ranges.
Wee Chin Wong, Jiali Li, Xiaonan Wang
semanticscholar   +1 more source

Emergence of the Biosimilar Sector and Opportunities of Developing Country Suppliers [PDF]

open access: yes, 2011
As biologic products begin to come off-patent, a market is emerging for biosimilars (also known as biogenerics or follow-on biologics). Firms from emerging countries such as India and China have dominated the production of active ingredients in ...
Huzair, Farah, Kale, Dinar
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

The Application of Lean Manufacturing for Operation Improvement: A Case Study of Black Cough Medicine Production in Indonesia

open access: yesAsian Journal of Technology Management, 2013
Nowadays, the pharmaceutical industry has a market tends to be unstable and volatile in meeting customer needs. This is due to the economic crisis that occurred in different parts of the world.
Pramadona Pramadona, Akbar Adhiutama
doaj   +2 more sources

Regional technology gap and innovation efficiency trap in Chinese pharmaceutical manufacturing industry

open access: yesPLoS ONE, 2020
Objective There is a huge technology gap between regions in Chinese pharmaceutical manufacturing industry, which is the reality that must be faced. However, most of the available researches on innovation efficiency are based on the logic of a given ...
Hongbo Lai, Hao Shi, Yang Zhou
semanticscholar   +1 more source

The Role of the Health Care Sector in Expanding Economic Opportunity [PDF]

open access: yes, 2007
This report provides an overview and critical assessment of the ways in which multinational pharmaceutical companies currently participate in expanding economic opportunities in developing countries.
Adeeb Mahmud, Marcie Parkhurst
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

3D printing and continuous flow chemistry technology to advance pharmaceutical manufacturing in developing countries

open access: yesArabian Journal of Chemistry, 2020
The realization of a downward spiralling of diseases in developing countries requires them to become self-sufficient in pharmaceutical products. One of the ways to meet this need is by boosting the local production of active pharmaceutical ingredients ...
C. Sagandira, M. Siyawamwaya, P. Watts
semanticscholar   +1 more source

Can NGOs Regulate Medicines Markets? Social Enterprise in Wholesaling, and Access to Essential Medicines. [PDF]

open access: yes, 2011
Citizens of high income countries rely on highly regulated medicines markets. However low income countries' impoverished populations generally struggle for access to essential medicines through out-of-pocket purchase on poorly regulated markets; results ...
Chaudhuri, Sudip   +2 more
core   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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