Results 51 to 60 of about 111,213 (213)

STRUCTURAL AND LOGIC ANALYSIS OF ANTIOXIDANTS AND ANTIHYPOXIC DRUGS

Кубанский научный медицинский вестник, 2018
Aim. The aim of this investigation was to establish the degree of saturation of the pharmaceutical market of Krasnodar Krai with antioxidants and antihypoxic drugs and to determine manufacturers of pharmaceutical substances for their production.Materials
I. I. PAVLYUCHENKO, N. M. BAT
doaj   +1 more source

Hydrothermal Humification of Biomass for Circular Carbon Management in Sustainable Agro‐Ecosystems

Advanced Science, EarlyView.
This article provides a comprehensive overview of biomass hydrothermal humification for building sustainable agro‐ecosystems. It examines the chemical transformation mechanisms and the functional benefits of the produced humic acids in soil remediation.
Ziyun Liu, Zonglu Yao, Yuanhui Zhang, Huiyan Zhang, Lixin Zhao   +4 more
wiley   +1 more source

Impact of National Centralized Drug Procurement policy on chemical pharmaceutical enterprises’ R&D investment: a difference-in-differences analysis in China

Frontiers in Public Health
ObjectiveThis study aimed to evaluate the impact of the National Centralized Drug Procurement (NCDP) policy on chemical pharmaceutical enterprises’ R&D investment and provide references for improving NCDP policy design and encouraging innovation in ...
Jiaming Li, Xinyue Zhang, Rui Wang, Keyao Cao, Luhui Wan, Xu Ren, Jinxi Ding, Jinxi Ding, Wei Li, Wei Li   +9 more
doaj   +1 more source

INFORMATIVE TECHNOLOGIES IN ESTIMATION OF T HE P HARMACEUTICAL MARKET

Medična Informatika ta Inženerìâ, 2013
An analytical study of methodologies of integral pharmaceutical market analysis is undertaken. It’s offered to use as an additional indicator of the pharmaceutical market state the trend of morbidity indexes of socially significant diseases.
L. Yu. Babintseva
doaj   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Iranian Pharmaceutical Industry Opportunities in Iraq

Journal of Pharmacoeconomics and Pharmaceutical Management, 2019
Background: The socioeconomic and political situation of Iraq has provided a wide and open market. Because of the weak pharmaceutical industry and war, Iraq has a huge demand for pharmaceutical and medical services; this country is a reliable market in ...
Ahmed Hayder Mohsin Al Iami, Saman Zartab, Mona Jaberidoost, Alireza Yektadoost, Shekoufeh Nikfar, Abbas Kebriaeezadeh   +5 more
doaj  

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Guideline for High‐Performance Liquid Chromatography Detection of Anthocyanins

AgriFood: Journal of Agricultural Products for Food, EarlyView.
ABSTRACT Anthocyanins, as water‐soluble natural pigments widely present in plants, have various biological activities such as antioxidation and anti‐inflammatory, and are widely used in the fields of food, cosmetics, and medicine. However, because of the presence of unstable phenolic hydroxyl groups in their structure, they are prone to degradation due
Zi‐Jun Xue, Xiao‐Lin Yu, Hao‐Yu Xue, Jin‐Long Tian   +3 more
wiley   +1 more source