Results 1 to 10 of about 93,206 (296)

A review of research methods for elucidating the microstructure of pharmaceutical preparations [PDF]

Journal of Pharmaceutical Analysis
The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes (CQAs), such as drug release, content uniformity, and stability, which greatly impact the safety and efficacy of drugs.
Peng Yan, Zhiyuan Hou, Jinsong Ding
doaj   +2 more sources

Effectiveness of pharmaceutical preparations of Periplaneta Americana (KangFuXin liquid) in the treatment of chronic gingivitis in children with orthodontic problems: A systematic review and meta-analysis of randomized controlled trials. [PDF]

Medicine (Baltimore)
Lin X, Niu S, Zhang J, Wang Y, Wu M, Chen Q.   +5 more
europepmc   +2 more sources

Drug repositioning: A bibliometric analysis

Frontiers in Pharmacology, 2022
Drug repurposing has become an effective approach to drug discovery, as it offers a new way to explore drugs. Based on the Science Citation Index Expanded (SCI-E) and Social Sciences Citation Index (SSCI) databases of the Web of Science core collection ...
Guojun Sun, Dashun Dong, Zuojun Dong, Qian Zhang, Hui Fang, Chaojun Wang, Shaoya Zhang, Shuaijun Wu, Yichen Dong, Yuehua Wan   +9 more
doaj   +1 more source

Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

Acta Pharmaceutica Sinica B, 2023
Fibrosis is one of the key factors that lead to the immune exclusion of solid tumors. Although degradation of fiber is a promising strategy, its application was still bottlenecked by the side effects of causing metastasis, resulting in the failure of ...
Jingwen Dong, Chenfei Zhu, Ying Huang, Quanhao Li, Jing Li, Zheng Wang, Yixin Wang, Zhanwei Zhou, Minjie Sun   +8 more
doaj   +1 more source

Investigation of excipients influence on rheological behaviour of hydrogels with dimethindene maleate and dexpanthenol: conditions of controlled shear rate

Current Issues in Pharmacy and Medical Sciences, 2021
Every year, the number of cases of hypersensitivity to insect bites increases. Thus, particular attention needs to be paid to the treatment of insect allergy in children, as scratching the bites can complicate the healing process and lead to infection ...
Popova Tetiana V., Kukhtenko Halyna P., Gladukh Ievgenii V., Kukhtenko Oleksandr S., Olkhovska Anzhela B.   +4 more
doaj   +1 more source

Synchrosqueezing Transform Based on Frequency-Domain Gaussian-Modulated Linear Chirp Model for Seismic Time–Frequency Analysis

Mathematics, 2023
The synchrosqueezing transform (SST) has attracted much attention as a post-processing technique since it was proposed. In recent years, improvements to SST have been made.
Pingping Bing, Wei Liu, Haoqi Zhang, Li Zhu, Guiping Zhu, Jun Zhou, Binsheng He   +6 more
doaj   +1 more source

Cost-utility analysis of centrally inserted totally implanted access port (PORT) vs. peripherally inserted central catheter (PICC) in the oncology chemotherapy

Frontiers in Public Health, 2022
BackgroundPeripherally inserted central catheter (PICC) and centrally inserted totally implanted access port (PORT) are two types of intravenous infusion devices that are widely used in clinical practice. PORTs are more expensive to insert than PICCs but
Guoliang Shao, Xiaoying Zhou, Shaoya Zhang, Shuaijun Wu, Yichen Dong, Zuojun Dong   +5 more
doaj   +1 more source

In vivo and in vitro neuroprotective effects of maca polysaccharide

Frontiers in Bioscience-Landmark, 2022
Objective: To explore the protective effect of MP on oxidative damage in vivo and in vitro. Methods: A mouse aging model was induced by intraperitoneal injection of D-galactose (D-gal), and pathological changes in the hippocampal ultrastructure were ...
Yi Zhou, Lemei Zhu, Haigang Li, Wenqing Xie, Juan Liu, Yuan Zhang, Yusheng Li, Chenggong Wang   +7 more
doaj   +1 more source

A fluorescence sensor for nitroreductase detection in hypoxic cells and zebrafish

Results in Chemistry, 2021
Nitroreductase (NTR) is a type of cytoplasmic enzyme that depends on flavin mononucleotide or flavin adenine dinucleotide, and that is widely present in tumor cells where it increases during hypoxia. NTR can effectively reduce aromatic nitro compounds to
Wan Sun, Mingqiong Tong, Guofeng Liu, Xiaoyue Wang, Na Fan, Xinfeng Song, Dongying Yang, Di Zhang   +7 more
doaj   +1 more source

Challenge of Politico-Economic Sanctions on Pharmaceutical Procurement in Iran: A Qualitative Study [PDF]

Iranian Journal of Medical Sciences, 2022
Background: Politico-economic sanctions over the recent years have led to significant challenges in the pharmaceutical supply chain (PSC) in Iran. Given the importance of the chain’s resilience for the health system and its impact on accessibility ...
Peivand Bastani, Zahra Dehghan, Seyyed Mansoor Kashfi, Hesam Dorosti, Mohammadtagi Mohammadpour, Gholamhossein Mehralian   +5 more
doaj   +1 more source