Results 41 to 50 of about 2,907,976 (379)

Spectrophotometric Determination of Nifedipine and Nicardipine in their Pharmaceutical Preparations

open access: yes, 2015
A sensitive and selective spectrophotometric method was developed for determination of nifedipine (NIF) and nicardipine (NIC) in their pharmaceutical preparations. The method based on a rapid reduction of the nitro to primary amino groups using zinc dust
M. Hamd   +4 more
semanticscholar   +1 more source

Effectiveness and safety of rivaroxaban or low-molecular-weight heparin in non-major orthopedic surgery: a meta-analysis of randomized controlled trials

open access: yesJournal of Orthopaedic Surgery and Research
Background Patients undergoing non-major orthopedic surgery often face an increased risk of venous thromboembolism due to the necessity of immobilization postoperatively. Current guidelines commonly recommend the use of low-molecular-weight heparin (LMWH)
Lemei Zhu   +4 more
doaj   +1 more source

Vitamin D supplementation for managing COVID-19 in patients with vitamin D deficiency: a systematic review and meta-analysis of randomised controlled trials

open access: yesBMJ Open
Objectives Vitamin D deficiency is prevalent among the population. Previous studies have shown that vitamin D supplementation might be useful for treating COVID-19 infection.
Xi Li   +6 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Fasting as an Adjuvant Therapy for Cancer: Mechanism of Action and Clinical Practice

open access: yesBiomolecules
The fundamental biological characteristics of tumor cells are characterized by irregularities in signaling and metabolic pathways, which are evident through increased glucose uptake, altered mitochondrial function, and the ability to evade growth signals.
Yichun Xie   +6 more
doaj   +1 more source

Recent Progress in Pharmaceutical Preparations [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1880
n ...
openaire   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Fabricating Oral Disintegrating Tablets Without Disintegrant Using Powder-Based 3D Printing

open access: yesPharmaceutics
Background: Powder-based 3D printing, an advanced additive manufacturing technique, can produce oral disintegrating tablets (ODTs) without disintegrants, creating larger-pored tablets via layer-by-layer powder stacking for better water absorption than ...
Jiu Wang   +6 more
doaj   +1 more source

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