Results 41 to 50 of about 2,773,562 (359)

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

Advanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal, Mimololorun Lucy Aiyelari, Martin Dirauf, Pavel Gurikov   +3 more
wiley   +1 more source

A fluorescence sensor for nitroreductase detection in hypoxic cells and zebrafish

Results in Chemistry, 2021
Nitroreductase (NTR) is a type of cytoplasmic enzyme that depends on flavin mononucleotide or flavin adenine dinucleotide, and that is widely present in tumor cells where it increases during hypoxia. NTR can effectively reduce aromatic nitro compounds to
Wan Sun, Mingqiong Tong, Guofeng Liu, Xiaoyue Wang, Na Fan, Xinfeng Song, Dongying Yang, Di Zhang   +7 more
doaj  

Deep learning for in vitro prediction of pharmaceutical formulations [PDF]

, 2018
Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning has been widely applied in many challenging domains because of its important capability of automatic feature ...
arxiv   +1 more source

Spectrophotometric determination of cefaclor in pharmaceutical preparations

Química Nova, 1999
A simple spectrophotometric method is proposed for the determination of cefaclor. The method involves alkaline hydrolysis of the drug in ammonia buffer solution at pH 10 to yield diketopiperazine-2,5-dione derivative and subsequent measurement at 340 nm. Beer's law is obeyed in the concentration range 1.8 - 55 mg/mL.
Ivama, Viviane M., Rodrigues, Letícia N. C., Guaratini, Cláudia C. I., Zanoni, Maria Valnice Boldrin   +3 more
openaire   +6 more sources

Spectrophotometric Determination of Nifedipine and Nicardipine in their Pharmaceutical Preparations

, 2015
A sensitive and selective spectrophotometric method was developed for determination of nifedipine (NIF) and nicardipine (NIC) in their pharmaceutical preparations. The method based on a rapid reduction of the nitro to primary amino groups using zinc dust
M. Hamd, A. Abdellatif, S. M. Derayea, O. Abdelmageed, H. Askal   +4 more
semanticscholar   +1 more source

Citric Acid: A Multifunctional Pharmaceutical Excipient

Pharmaceutics, 2022
Citric acid, a tricarboxylic acid, has found wide application in the chemical and pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally friendly chemistry.
M. Lambros, Thac (Henry) Tran, Q. Fei, M. Nicolaou   +3 more
semanticscholar   +1 more source

Effectiveness and safety of rivaroxaban or low-molecular-weight heparin in non-major orthopedic surgery: a meta-analysis of randomized controlled trials

Journal of Orthopaedic Surgery and Research
Background Patients undergoing non-major orthopedic surgery often face an increased risk of venous thromboembolism due to the necessity of immobilization postoperatively. Current guidelines commonly recommend the use of low-molecular-weight heparin (LMWH)
Lemei Zhu, Bohua Zhu, Pingping Bing, Mingxu Qi, Binsheng He   +4 more
doaj   +1 more source

Fabricating Oral Disintegrating Tablets Without Disintegrant Using Powder-Based 3D Printing

Pharmaceutics
Background: Powder-based 3D printing, an advanced additive manufacturing technique, can produce oral disintegrating tablets (ODTs) without disintegrants, creating larger-pored tablets via layer-by-layer powder stacking for better water absorption than ...
Jiu Wang, Shunfang Liu, Minmei Lin, Peihong Chen, Huagui Yi, Zhufen Lv, Yuanfen Liu   +6 more
doaj   +1 more source

Modular, Multi-Robot Integration of Laboratories: An Autonomous Solid-State Workflow for Powder X-Ray Diffraction [PDF]

arXiv, 2023
Automation can transform productivity in research activities that use liquid handling, such as organic synthesis, but it has made less impact in materials laboratories, which require sample preparation steps and a range of solid-state characterization techniques.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source