Results 41 to 50 of about 1,040,359 (356)

Xoconostle fruit (Opuntia matudae Scheinvar cv. Rosa) by-products as potential functional ingredients [PDF]

, 2015
There is a lack of information on the potential use of xoconostle cultivars as sources of antioxidants for food, pharmaceutical and colorant industries.
Barros, Lillian, Ferreira, Isabel C.F.R., Morales, Patricia, Ramírez-Moreno, Esther, Santos-Buelga, Celestino   +4 more
core   +1 more source

DOMESTIC AND FOREIGN EXPERIENCE ANALYSIS OF PLANNING AND REGULATORY RESEARCH IN PHARMACEUTICALS

Кубанский научный медицинский вестник, 2017
Aim. To conduct an analysis of the management of innovation activities for innovative medicines market launch in Russia and abroad.Material and Methods.
A. A. SEMIN
doaj   +1 more source

Glucosamine/L-lactide copolymers as potential carriers for the development of a sustained rifampicin release system using Mycobacterium smegmatis as a tuberculosis model

Heliyon, 2019
The present study aims at developing a new, ultrafine particle-based efficient antibiotic delivery system for the treatment of tuberculosis. The carrier material to make the rifampicin (RIF)-loaded particles is a low molecular weight star-shaped polymer ...
Jorge Ragusa, Daniela Gonzalez, Sumin Li, Sandra Noriega, Maciej Skotak, Gustavo Larsen   +5 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling

iScience
Summary: Arthropod venoms contain bioactive molecules attractive for biomedical applications. However, few of these have been isolated, and only a tiny number has been characterized.
Pelin Erkoc, Susanne Schiffmann, Thomas Ulshöfer, Marina Henke, Michael Marner, Jonas Krämer, Reinhard Predel, Till F. Schäberle, Sabine Hurka, Ludwig Dersch, Andreas Vilcinskas, Robert Fürst, Tim Lüddecke   +12 more
doaj   +1 more source

Potential protective function of the sterol regulatory element binding factor 1–fatty acid desaturase 1/2 axis in early-stage age-related macular degeneration

Heliyon, 2017
Age-related macular degeneration (AMD) is the most common cause of vision loss in elderly individuals throughout the developed world. Inhibitors of vascular endothelial growth factor have been successfully used to treat choroidal neovascularization in ...
Yoshifumi Ashikawa, Yuhei Nishimura, Shiko Okabe, Yumi Sato, Mizuki Yuge, Tomoko Tada, Haruka Miyao, Soichiro Murakami, Koki Kawaguchi, Shota Sasagawa, Yasuhito Shimada, Toshio Tanaka   +11 more
doaj   +1 more source

Avenanthramides as lipoxygenase inhibitors

Heliyon, 2020
Avenanthramides (AVAs) present in oats are amides of anthranilic and cinnamic acids. AVAs are potent antioxidants and have anti-inflammatory properties.
Rikard Landberg, Kerstin Sunnerheim, Lena H. Dimberg   +2 more
doaj   +1 more source

Freeform Bioprinting of Liver Encapsulated in Alginate Hydrogels Tissue Constructs for Pharmacokinetic Study [PDF]

, 2006
An in vitro model that can be realistically and inexpensively used to predict human response to various drug administration and toxic chemical exposure is needed.
Chang, R., Culbertson, C., Gonda, S., Holtorf, H., Starly, B., Sun, W.   +5 more
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Pharmacy Curriculum Outcomes Assessment (PCOA) as Predictor of Performance on NAPLEX [PDF]

, 2015
Objectives: The purpose of the study was to respond to students’ inquiry regarding the relationship between student performance on the PCOA administered in early spring of the P3 year and performance on the NAPLEX administered post-graduation.
Hutchinson, David, Lenhard, Lalani, Souza, Jane M.   +2 more
core