Results 41 to 50 of about 1,073,791 (260)

Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

Heliyon, 2019
Anxiety disorders, depression and pain are highly prevalent pathologies. Their pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to develop more effective drugs with fewer adverse reactions.Chalcones are one of the ...
Josefina Higgs, Cristina Wasowski, Alejandra Marcos, Marko Jukič, Carlos Humberto Paván, Stanislav Gobec, Felicitas de Tezanos Pinto, Natalia Colettis, Mariel Marder   +8 more
doaj   +1 more source

2018 High Sierra Leadership Expedition [PDF]

, 2018
STEP Category: Leadership2018 High Sierra Leadership Expedition Presentation by Lauren Kobasuk.The Ohio State University Second-year Transformational Experience Program (STEP)Academic Major: Pharmaceutical ...
Kobasuk, Lauren
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Dinutuximab beta effectively treats Ewing sarcoma when combined with chemotherapy

iScience
Summary: Ewing sarcoma is a rare and aggressive cancer of the bone and soft tissues primarily affecting children and young adults. Prognosis for patients with metastatic or recurrent disease remains poor despite intensive multimodal therapy, highlighting
Roberta Frapolli, Marina Meroni, Ezia Bello, Lorenza Pirona, Elisa Callegari, Valentina Kebede, Isabella Pellerani, Simone Canesi, Eugenio Scanziani, Uta Dirksen, Patrizia Angelico, Stefano Biondi, Matteo Malinverno   +12 more
doaj   +1 more source

Recent advances in pharmaceutical sciences VII [PDF]

, 2017
The E-book series Recent Advances in Pharmaceutical Sciences reports research contributions from different areas of the multidisciplinary field of Pharmaceutical Sciences.
Feliu José, Carlos, Muñoz-Torrero López-Ibarra, Diego, Riu Aumatell, Montserrat   +2 more
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Phellopterin isolated from Angelica dahurica reduces blood glucose level in diabetic mice

Heliyon, 2018
Insulin resistance is the critical condition for the development of metabolic syndromes including type II diabetes and heart disease. To investigate the active components of Angelica dahurica root which is known to increase insulin sensitivity, its ...
Hyo Sang Han, Hyelin Jeon, Se Chan Kang
doaj   +1 more source

Patent Trend in Research Centers at Cibinong Science and Technology Park Surrounding for Determining Technology Focus [PDF]

, 2017
. Focusing in a specific technology sector would be a great strategy for early developed Science and Technology Park (STP) especially in Indonesia. Each STP has its own concept considering the resources and technology supply.
Wicaksono, A. (Adityo), Yaniar, H. (Harini)   +1 more
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Antibacterial activities of green tea crude extracts and synergistic effects of epigallocatechingallate (EGCG) with gentamicin against MDR pathogens

Heliyon, 2019
Plant extracts and their purified compounds were examined for synergistic antimicrobial activity using selected multi-drug resistant (MDR) pathogens.
Md. Anowar Khasru Parvez, Karabi Saha, Juairia Rahman, Rahath Ara Munmun, Md. Atikur Rahman, Shuvra Kanti Dey, Md. Shahedur Rahman, Sohidul Islam, Mohammad Hossain Shariare   +8 more
doaj   +1 more source

Aid conditionalities, international Good Manufacturing Practice standards and local production rights: a case study of local production in Nepal [PDF]

, 2015
© 2015 Brhlikova et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium ...
A Abdo-Rabbo, AH Meshkini, Allyson M. Pollock, B Shakya, B Shrestha, DA Grimes, DDA, E Toledo, ES Pinheiro, GAO, H Dixit, HSSP, I Harper, Ian Harper, J Abraham, J-M Guimier, K Losse, K Morimoto, K Timmermans, M Santhosh, Madhusudan Subedi, MHP, Nabin Rawal, P Brhlikova, P Trouiller, P Trouiller, PEPFAR, Petra Brhlikova, PG Mujinja, S Budhathoki, S Chaudhuri, S Hill, S Palaian, Samita Bhattarai, SAWTEE, Thapa, UNCTAD, UNIDO, W Kaplan, WA Kaplan, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO WHO   +47 more
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Alteration in plasma and striatal levels of d-serine after d-serine administration with or without nicergoline: An in vivo microdialysis study

Heliyon, 2017
Aims: d-Serine (d-Ser), a co-agonist of N-methyl-d-aspartate receptor (NMDAR), is effective for treating schizophrenia. The present study investigated changes in plasma and striatal d-Ser levels in Sprague-Dawley (SD) rats after intraperitoneal d-Ser ...
Mayu Onozato, Hiromi Nakazawa, Katsuyuki Ishimaru, Chihiro Nagashima, Minori Fukumoto, Hitomi Hakariya, Tatsuya Sakamoto, Hideaki Ichiba, Takeshi Fukushima   +8 more
doaj   +1 more source

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

Heliyon, 2018
Androgen biosynthesis in males occurs to a large extent in testicular Leydig cells. This study focused on the evaluation of three murine Leydig cell lines as potential screening tool to test xenobiotics interfering with gonadal androgen synthesis.
Roger T. Engeli, Cornelia Fürstenberger, Denise V. Kratschmar, Alex Odermatt   +3 more
doaj   +1 more source