Results 71 to 80 of about 483,083 (302)
Has the European Union Achieved a Single Pharmaceutical Market? [PDF]
This paper explores price differences in the European Union (EU) pharmaceutical market, the EU's fifth largest industry. With the aim of enhancing quality of life along with industry competitiveness and R&D capability, many EU directives have been ...
Gabriel Picone +2 more
core
Developing a FIP handbook for implementing competency-based education in pharmacy education
, 2022 Competency-based education (CBE) is a viable educational approach to close a training gap between ever-changing health challenges and pharmacy and pharmaceutical education curricula.
Darwish, Rula +7 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Pharmaceutical Analytics at the Institute of Pharmaceutical Sciences
CHIMIA, 2004 Some of our research activities in Pharmaceutical Analysis, Irradiation of Pharmaceutical Drug Substances, Development of Monographs and new Methods on Pharmaceutical Substances for the European- and Swiss Pharmacopoeia are described.
openaire +3 more sources
Computational pharmaceutical materials science [PDF]
Journal of Cheminformatics, 2014 Pharmaceutical materials science addresses the physical solid-state properties of pharmaceutical products, such as solubility and stability of crystal structures. Especially the different properties of different polymorphs, salts and hydrates of an Active Pharmaceutical Ingredient (API) are of interest, although more recently the amorphous state has ...
openaire +2 more sources
Benchmarking and visualising the knowledge base of pharmaceutical firms (1995-2009)
, 2011 The rise of biotechnology in the 1970s ushered in a change in innovation strategies in the pharmaceutical industry. The vertically-integrated company become more reliant on a distributed innovation structure in which large corporations integrate the ...
Hopkins, Michael-M. +4 more
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Evaluation of the Pharmaceutical Industry Investment Program [PDF]
With the expiry of the Pharmaceutical Industry Investment Program (PIIP) in 2004, the Commission was asked to conduct an evaluation of the program’s rationale, effectiveness and efficiency. The study commenced in August 2002.
Productivity Commission
core
, 2023 The aim: development of methodological approaches to assessing the digital maturity of the logistics activity of a pharmaceutical enterprise and elaboration of the proposed methodology on the example of those domestic enterprises that have a developed ...
Ольга Вікторівна Olga Posilkina Посилкіна +9 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source