Results 101 to 110 of about 4,705,551 (307)

Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation

open access: yesHeliyon, 2017
Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date, only a few studies have reported that CysLTs promote chemotactic activity of human eosinophils in ...
Hideaki Shirasaki   +2 more
doaj  

Recommendations for the Use of Disease‐Modifying Antirheumatic Drugs in Pregnancy and Reproductive Health for Patients With Rheumatic Disease: A Scoping Review

open access: yesArthritis Care &Research, EarlyView.
Objective Autoimmune rheumatic diseases commonly affect individuals of childbearing age, with historically increased adverse pregnancy outcomes in this group. The advent of disease‐modifying antirheumatic drugs (DMARDs) has fostered more suitable conditions for pregnancy; however, this is accompanied by challenges in ensuring safe use in reproductive ...
Athena Chin   +4 more
wiley   +1 more source

Solubility; still a challenging subject in pharmaceutical sciences

open access: yesVitae, 2010
Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their ...
Abolghasem Jouyban
doaj   +2 more sources

Association Between Sleep Disturbance and Subsequent Pain Interference in Patients With Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective This study investigated whether sleep disturbance can predict the extent to which pain interferes with daily functioning in patients with early rheumatoid arthritis (RA). Methods Data were from adults with early RA (joint symptoms ≤12 months) enrolled in the Canadian Early Arthritis Cohort between 2016 and 2023.
Burcu Aydemir   +16 more
wiley   +1 more source

Agreement of administrative pharmacy dispensing with self‐reported use of oral prednisone in US Veterans with rheumatoid arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace   +16 more
wiley   +1 more source

Time trends and predictors of gout remission over six years

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah   +5 more
wiley   +1 more source

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