Results 101 to 110 of about 1,013,409 (346)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Policy Analysis Of Iranian Pharmaceutical Sector; A Qualitative Study

Risk Management and Healthcare Policy, 2019
Farbod Ebadi Fardazar,1 Ali Sarabi Asiabar,2 Hossein Safari,1 Mojgan Asgari,3 Ali Saber,4 Amir Ali Ebadi Fard Azar5 1School of Public Health, Health Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran; 2School of Health ...
Ebadi Fardazar F, Sarabi Asiabar A, Safari H, Asgari M, Saber A, Ebadi Fard Azar AA   +5 more
doaj  

Synergistic Cytotoxic Effect from Combination of Wedelolactone and Cisplatin in HeLa Cell Line: A Novel Finding

Drug Design, Development and Therapy, 2020
Sadia Sarwar,1,2 Jun Qing Yu,1 Humaira Nadeem,3 Fazlul Huq1 1Discipline of Biomedical Sciences, Sydney Medical School, The University of Sydney, Cumberland Campus, Sydney, NSW, Australia; 2Department of Pharmacognosy, Riphah Institute of Pharmaceutical ...
Sarwar S, Yu JQ, Nadeem H, Huq F
doaj  

Symposium on information science. 8. An approach to the automated handling of chemical-biological data in a pharmaceutical firm [PDF]

, 1965
C W Durachta, Colin Schenk, Richard Dick, F M Sturtevant   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The Trend of Pharmaceutical Research in Iran Compared to Middle East and North Africa: A Scientometrics Study

مدیریت اطلاعات سلامت, 2010
Introduction: The purpose of this study was to evaluate the Iranian trend of research in pharmaceutical sciences published in international publication and to compare it with that in other countries in the Middle East and North Africa in 1996-2006 ...
Bita Mesgarpour, Arash Etemadi, Akbar Fotouhi, Abbas Kebriaeezadeh, Masoud Younesian   +4 more
doaj  

The opioid receptor: emergence through millennia of pharmaceutical sciences. [PDF]

Front Pain Res (Lausanne), 2023
Fairbanks CA, Peterson CD.
europepmc   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

FEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq, Holly Matthews, Daniya Abedalreza, Faten Yahya, Matthew Allan Jones   +4 more
wiley   +1 more source

Risk factors and prescription patterns analysis for macrolide-resistant Mycoplasma pneumoniae pneumonia in children

iScience
Summary: First-line macrolide therapy is encountering challenges due to the escalating incidence of macrolide-resistant Mycoplasma pneumoniae pneumonia (MRMPP).
Yun Lu, Wen-jing Li, Xuan-xuan Wang, An-qi Huang, Hong Cheng   +4 more
doaj   +1 more source