Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date, only a few studies have reported that CysLTs promote chemotactic activity of human eosinophils in ...
Hideaki Shirasaki+2 more
doaj
Objective Autoimmune rheumatic diseases commonly affect individuals of childbearing age, with historically increased adverse pregnancy outcomes in this group. The advent of disease‐modifying antirheumatic drugs (DMARDs) has fostered more suitable conditions for pregnancy; however, this is accompanied by challenges in ensuring safe use in reproductive ...
Athena Chin+4 more
wiley +1 more source
Solubility; still a challenging subject in pharmaceutical sciences
Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their ...
Abolghasem Jouyban
doaj +2 more sources
Seventy five years of the School of Veterinary Medicine, now University of Veterinary and Pharmaceutical Sciences [PDF]
John Konrad
openalex +1 more source
Objective This study investigated whether sleep disturbance can predict the extent to which pain interferes with daily functioning in patients with early rheumatoid arthritis (RA). Methods Data were from adults with early RA (joint symptoms ≤12 months) enrolled in the Canadian Early Arthritis Cohort between 2016 and 2023.
Burcu Aydemir+16 more
wiley +1 more source
[The Research Status and Future Direction of Pharmaceutical Sciences and Pharmaceutical Materials in China]. [PDF]
Zhang ZR.
europepmc +1 more source
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace+16 more
wiley +1 more source
Time trends and predictors of gout remission over six years
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah+5 more
wiley +1 more source
Science Symposia at the British Pharmaceutical Conference [PDF]
Joseph P. Chamberlain
openalex +1 more source
Chronic Blockade of the Melanocortin 4 Receptor Subtype Leads to Obesity Independently of Neuropeptide Y Action, with No Adverse Effects on the Gonadotropic and Somatotropic Axes**This work was supported by grants from the Swiss National Research Science Foundation (31–39729-93, 31–55732-98, and 32–04912 3–97) and in part by Ferring Pharmaceuticals Ltd. Research Laboratories. [PDF]
Paula Raposinho+5 more
openalex +1 more source