Results 51 to 60 of about 1,013,409 (346)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Prediction of the permeability of neutral drugs inferred from their solvation properties [PDF]

open access: yes, 2015
Determination of drug absorption is an important component of the drug discovery and development process in that it plays a key role in the decision to promote drug candidates to clinical trials.
Milanetti, Edoardo   +2 more
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Impact of Surface Tension in Pharmaceutical Sciences

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2009
Surface chemistry has a large influence in many industries. In the life sciences, surface area is gaining importance in the characterization of materials during their development, formulation and manufacturing.
Anahita Fathi Azarbayjani   +2 more
doaj   +1 more source

Recent Trends in Ayurvedic Pharmacy Education in India [PDF]

open access: yes, 2008
We wish to train the student perusing career in Ayurvedic Pharmaceutical Sciences both at traditional and molecular levels. The Ayurvedic/herbal /nutraceutical market is hot and it is right time to improve educational standards in Ayurvedic ...
Bhagel, Saurabh Singh, Singh, Amritpal
core   +1 more source

Scientific and Practical Approaches to Form the List of Social-psychological Characteristics for Pharmacy Specialist [PDF]

open access: yes, 2019
Nowadays according to employers, pharmacy specialist should be not only competent professional, but versed in the consumer psychology and result oriented, at the same time, i.e.
Barnatovych, S. (Svitlana)   +3 more
core   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Ayurvedic Pharmaceutical Sciences: Challenges Ahead [PDF]

open access: yes, 2008
Ayurvedic Pharmaceutical Sciences (APS) is an upcoming discipline. Ayurvedic pharmacy (AP) has always been looked upon as traditional subject having limited value in modern era of pharmaceutical sciences.
Singh, Amritpal
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Introducing an Undergraduate Degree of Cosmetic Science and Formulation Design within a College of Pharmacy

open access: yesINNOVATIONS in Pharmacy, 2017
As a unique and versatile undergraduate degree program, a Bachelor of Science in Pharmaceutical Sciences (BSPS) is offered by a number of colleges/schools of pharmacy.
Gabriella Baki   +2 more
doaj   +1 more source

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