Results 61 to 70 of about 603,038 (294)

ฤทธิ์ยับยั้งเอนไซม์ไทโรซิเนสและฤทธิ์ต้านเชื้อจุลินทรีย์จากสมุนไพรไทย [PDF]

, 2010
Thesis (M.Pharm., Pharmaceutical Sciences)--Prince of Songkla University ...
Imron Meechai
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation

Heliyon, 2017
Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date, only a few studies have reported that CysLTs promote chemotactic activity of human eosinophils in ...
Hideaki Shirasaki, Etsuko Kanaizumi, Tetsuo Himi   +2 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The Future of Pharmaceutical Manufacturing Sciences

Journal of Pharmaceutical Sciences, 2015
The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial-scale manufacturing of complex drug delivery systems (DDSs) using the existing technologies is challenging.
Rantanen, Jukka, Khinast, Johannes
openaire   +3 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

องค์ประกอบทางเคมีจากฟองน้ำสกุล Halichondria และฟองน้ำสกุล Aplysinopsis

, 2010
Thesis (M.Pharm., Pharmaceutical Sciences)--Prince of Songkla University ...
Phatchareephorn Chatakul
core  

Scientific Authority in Iranian Pharmaceutical Sciences Research Centers: The Results of a Decade Research Evaluation: Scientific Authority in Pharmaceutical Research Center

The scientific authority refers to social power of scientific knowledge, in different sciences.  The aim of this study is to present the role of Iranian pharmaceutical research centers in scientific authority based on research evaluation for a decade ...
Falahat, Katayoun, Ashouri, Sahar, Baradaran Eftekhari, Monir   +2 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Intraoperative hydroxyethyl starch 130/0.4 infusion and graft function following donation-after-cardiac-death kidney transplantation

iScience
Summary: Whether intraoperative hydroxyethyl starch (HES) 130/0.4 infusion affects delayed graft function (DGF) after donation-after-cardiac-death (DCD) kidney transplantation remains uncertain.
Yang Zhang, Ke Peng, Linkun Hu, Jing Yan, Yuhua Huang, Hong Liu, Jiaqiang Zhang, Mingyang Sun, Xisheng Shan, Fuhai Ji   +9 more
doaj   +1 more source