Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
The pharmaceutical distribution chain in the European Union: structure and impact on pharmaceutical prices [PDF]
In an environment characterised by fragmentation in the market structure of wholesale and retail entities, significant diversity in terms of remuneration schemes as well as regulations pertaining to operational features of wholesale and retail entities ...
Kanavos, Panos+2 more
core
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo+3 more
wiley +1 more source
The Impact of Pharmaceutical Services Availability on Travellers
Vacationing and travelling overall may be considered a healthy lifestyle, which might help fighting current epidemics such as depression or heart disease. In some cases, travellers ight need to use Pharmaceutical Services (PhaS) provided by Community Pharmacies, which might impact their health and wellbeing during their stay.
De Sousa-Coelho, Ana Luísa+2 more
openaire +3 more sources
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach+4 more
wiley +1 more source
Pharmacists’ Experiences on Adverse Drug Reactions in Saudi Arabia: A Cross-Sectional Study
Background and objectives: As part of Vision 2030, Saudi Arabia aims to strengthen its healthcare system by enhancing efficiency, reducing medical errors, and ensuring drug safety.
Dalal Salem Bakheit Aldossari+7 more
doaj +1 more source
Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi+8 more
wiley +1 more source
BackgroundThe World Health Organization (WHO) has recommended strategies and actions to enhance awareness and understanding of AMR. Gaps in AMR awareness remain in Jordan, particularly among the youth.AimTo describe our programmatic approach to AMR ...
Basmah Qenab+8 more
doaj +1 more source
Knowledge, Perception, and Readiness of Indonesian Pharmacists for the Implementation of Telepharmacy-Based Pharmaceutical Services in Indonesia. [PDF]
Wathoni N+6 more
europepmc +1 more source
The U.S.-Singapore Free Trade Agreement: Effects After Five Years [PDF]
[Excerpt] The U.S.-Singapore Free Trade Agreement (FTA) (P.L. 108-78) went into effect on January 1, 2004. This report provides an overview of the major trade and economic effects of the FTA over the three years ending in 2006.
Nanto, Dick K
core +2 more sources