Results 161 to 170 of about 130,335 (313)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Pharmacist-Led Hepatitis C Diagnosis and Rapid Management-In Community (PHARM-C): Results From a Phase IV Nonblinded Randomised Controlled Trial. [PDF]

J Viral Hepat
Biondi MJ, Capraru CI, Harper B, Gill P, Dale CH, Nicolle J, Chung D, Boutrous M, Wilson AD, Lam V, Morkos D, Barber B, Usoro MA, Mendlowitz AB, Shah H, Fontaine G, Hansen B, Feld JJ.   +17 more
europepmc   +1 more source

Emphasizing the Role of Pharmacist as a Researcher: The Lebanese Order of Pharmacists’ Perspective

, 2019
Souheil Hallit, Aline Hajj, Hala Sacre, Rony M. Zeenny, Marwan Akel, Georges Sili, Pascale Salameh   +6 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The impact of pharmacist intervention on FIM gain in patients with musculoskeletal disorders in Kaifukuki rehabilitation wards. [PDF]

Jpn J Compr Rehabil Sci
Fujihara H, Kishimoto M, Kose E, Shinonaga H, Tanaka E, Nakamichi M, Mizokami F.   +6 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The impact of quarantine and isolation during COVID-19 lockdown on the mental health of affected students at the University of Limpopo, South Africa

Global Journal of Medicine and Public Health
Background The COVID-19 pandemic has caused widespread problems with the general psychological state, including signs of depression and anxiety among the population.
Teresa-Anne Mashego, Tiisetso Aubrey Chuene, Seponono Raisibe Mampa, Thembelihle Sam Ntuli   +3 more
doaj  

Pharmacists' Role in HPV Vaccine Uptake Among Women: A Scoping Review of Interventions and Barriers. [PDF]

Int J Womens Health
Hanifa AN, Insani WN, Abdulah R.
europepmc   +1 more source

The roles of community pharmacists in cardiovascular disease prevention and managemen

, 2011
Johnson George
openalex   +1 more source