Results 161 to 170 of about 130,799 (313)

Impact of Clinical Pharmacists’ Recommendations on a Proton Pump Inhibitor Taper Protocol in an Ambulatory Care Practice [PDF]

, 2013
Andrew W. Bundeff, Kathy Zaiken
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

<i>AI-Enabled Sacramento Public Health (SACPH) App:</i> A Reproducible AI-Based Method for Population-to-Practice Reasoning in Foundational Sciences in Pharmacy Education. [PDF]

Pharmacy (Basel)
Malhotra A.
europepmc   +1 more source

Pharmacist educators: empowering pharmacists for medical education

European Journal of Hospital Pharmacy
Shih-Chieh Shao, Kai-Cheng Chang, Shu-Chen Liao, Yu-Che Chang, Rong-Nan Chien   +4 more
openaire   +3 more sources

Role of community pharmacy and pharmacists in self care in Sweden

, 2023
Tommy Westerlund, Lars‐Åke Söderlund
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Perceptions and Expectations of Pharmacist Interventions in Adverse Event Management During Drug Therapy for Metastatic Renal Cell Carcinoma: A Cross-Sectional Survey in Japan. [PDF]

Cancers (Basel)
Wako T, Kimura G, Fujii Y, Osawa T, Uchitomi Y, Honda K, Kondo M, Otani A, Mitsuda Y, Shinohara N.   +9 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The impact of quarantine and isolation during COVID-19 lockdown on the mental health of affected students at the University of Limpopo, South Africa

Global Journal of Medicine and Public Health
Background The COVID-19 pandemic has caused widespread problems with the general psychological state, including signs of depression and anxiety among the population.
Teresa-Anne Mashego, Tiisetso Aubrey Chuene, Seponono Raisibe Mampa, Thembelihle Sam Ntuli   +3 more
doaj  

Introduction of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) nasal polymerase chain reaction testing combined with pharmacist ordering and intervention reduces anti-MRSA antibiotic use in a multi-hospital system. [PDF]

Antimicrob Steward Healthc Epidemiol
Collins CD, Gupta C, Chou J, Shen J, Murphy H.   +4 more
europepmc   +1 more source