Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Exploring patient satisfaction with community pharmacy services in the United Arab Emirates: Implications for quality improvement. [PDF]
Kharaba Z +14 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Protected learning time in community pharmacy and possibilities for upscaling: an exploratory study in Wales, UK. [PDF]
Bartlett S, Bullock A.
europepmc +1 more source
Prescriptions for Excellence in Health Care Spring 2011 Download PDF [PDF]
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Good Practices and Challenges in the Collaboration of Pharmacists with General Practitioners-A Scoping Review. [PDF]
Gavazova E, Atliev K, Kafalova D.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Correction: Pharmacist input to depression screening and management in patients with diabetes: a systematic review. [PDF]
Al-Hawamdeh MI +4 more
europepmc +1 more source
Seattle-King County Pharmaceutical Society and Greater Seattle Retail Drug Association, Inc. and Pharmacists and Retail Drug Stores Employees Union, Local 330 (1968) [PDF]
core +1 more source

