Results 61 to 70 of about 130,799 (313)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Study on the Effects of Chloroformic Extract of Securigera Securidaca on Serum Glucose Level and Liver Glycogen Content of Mice [PDF]
Although Securigera securidaca (Ss) has long been known for its hypoglycemic effect, the precise nature of its effective component(s) and the involved mechanisms have not been investigated yet.
S Zahedi-Asl, H Marahel, B Zaree
doaj
A Smart mobile health intervention: Improving hypertension self-management through whatsapp-delivered video education [PDF]
Hypertension remains a leading global health challenge, particularly in low-resource settings where access to health education is limited. This study aimed to evaluate the effectiveness of a video-based educational intervention delivered via WhatsApp in ...
Akhyar Zeda Kumala +2 more
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Pharmacist working conditions [PDF]
I applaud the British Columbia College of Pharmacists for supporting an examination of pharmacist working conditions.1 This issue has been swept under the table for far too long, and it isn’t surprising to see that this study suggests that almost a third of pharmacists feel they are practising in an unsafe work environment. Almost 2 years ago, I had to
openaire +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source

