Results 291 to 297 of about 74,509 (297)
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Pharmacogenomics in Thrombosis
2010Inherited or acquired genetic abnormalities play a major role in thromboembolic complications. The goal of pharmacogenomics is to tailor medications to an individual's genetic makeup in order to improve the benefit-to-risk ratio. Significant findings have been documented showing the effect of certain genetic variations (e.g., in CYP2C9 and VKORC1) on ...
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Pharmacogenomics of adrenoceptors
Pharmacogenomics, 2004Adrenoceptors (ARs) consist of nine subtypes (alpha(1A)-, alpha(1B)-, alpha(1D)-, beta(1)-, beta(2)-, beta(3)-, alpha(2A)-, alpha(2B)- and alpha(2C)-AR), which are involved in a wide spectrum of physiological functions and are the site of action for a considerable percentage of currently prescribed therapeutics.
Christodoulos S. Flordellis +3 more
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Ethnopsychopharmacology and Pharmacogenomics
2013Significant differences in response to psychotropic drugs are observed in various ethnic and cultural groups. Ethnopsychiatry is the study of how culture and genetic differences in human groups determine and influence the response to psychotropic agents. Meanwhile, pharmacogenomics studies the influence of genetic variations in the response of patients
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2014
Due to genetic variations, different individuals respond differently to the same dosage of a drug. Although pharmacogenomics is a vast topic with several excellent books in the literature, this chapter will focus on basic pharmacogenomics such as genetic variations in the activities of CYP2D6, CYP2C9, CYP2C19, and drug transporters that affect the ...
Amitava Dasgupta, Amer Wahed
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Due to genetic variations, different individuals respond differently to the same dosage of a drug. Although pharmacogenomics is a vast topic with several excellent books in the literature, this chapter will focus on basic pharmacogenomics such as genetic variations in the activities of CYP2D6, CYP2C9, CYP2C19, and drug transporters that affect the ...
Amitava Dasgupta, Amer Wahed
openaire +2 more sources