Results 51 to 60 of about 37,453 (180)

Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley   +1 more source

LC‐MS‐Based Annotation of Bioactive Metabolites From Streptomyces fimicarius‐ghR Against the Common Scab Pathogen Using Molecular Networking

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
EtOAc extract of Streptomyces fimicarius‐ghR exhibited inhibitory activity against Streptomyces sp. FG1(MIC: 0.3 mg/mL). The LC‐QTOF‐ESI‐MS/MS analysis of the extract, followed by data analysis through molecular networking (GNPS), led to the annotation of mycosubtilins, cyclic surfactins, and linear surfactins.
Maryam Ramezani‐Moghadam   +6 more
wiley   +1 more source

Bioactive Compounds and Antidiabetic Properties of Launaea mucronata Hydroethanolic Extract: Phytochemical and Pharmacological Insights

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Phytochemical and biological profiling of Launaea mucronata aerial parts reveals six bioactive constituents alongside potent antioxidant and antidiabetic properties. The hydroethanolic extract inhibits key carbohydrate‐metabolizing enzymes and exerts marked hypoglycemic and insulinotropic effects with histological restoration of metabolic organs in ...
Amira Mohamed   +5 more
wiley   +1 more source

Pharmacognostic outlooks on medical herbs of Sasang typology

open access: yesIntegrative Medicine Research, 2017
The purpose of this study was to review the pharmacognostic characteristics of Sasang type-specific medical herbs and suggest biological mechanisms that might be related to the personalized treatment of the East. Major compounds and their pharmacological
Su Hye Lim   +4 more
doaj   +1 more source

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang   +4 more
wiley   +1 more source

Systems Pharmacology and Multitarget Modulation of Letrozole–HFD‐Induced Polycystic Ovarian Syndrome by Fruit Pulp of Prunus armeniaca

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Integrated systems pharmacology and in vivo evaluation reveal that hydroalcoholic extract of fruit pulp of Prunus armeniaca (HAE of FPPA) ameliorates letrozole–HFD‐induced PCOS through multitarget modulation. Network analysis identifies 105 shared targets enriched in PI3K/Akt, MAPK, HIF‐1, and inflammatory pathways, while treatment improves hormonal ...
Ratna Priya   +4 more
wiley   +1 more source

Scientific basis of the development and standardization of herbal medicines

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The present paper conceptually considers scientific approaches to standardization of starting materials of herbal origin and herbal medicinal products.
I. A. Samylina   +2 more
doaj  

Medicinal Plants from Near East for Cancer Therapy

open access: yesFrontiers in Pharmacology, 2018
Background: Cancer is one of the major problems affecting public health worldwide. As other cultures, the populations of the Near East rely on medicinal herbs and their preparations to fight cancer.Methods: We compiled data derived from historical ...
Mohammad S. Abu-Darwish   +2 more
doaj   +1 more source

A Case of Remarkable Improvement in Dizziness and Lightheadedness in an Elderly Patient Treated With Goshajinkigan

open access: yes
Traditional &Kampo Medicine, Volume 13, Issue 3, December 2026.
Akiko Kikuchi   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy