Results 91 to 100 of about 219,082 (266)

Pharmacokinetic parameters quantification in DCE-MRI for prostate cancer [PDF]

open access: yesarXiv, 2023
Tumor vascularity detection and quantification are of high relevance in the assessment of cancer lesions not only for disease diagnostics but for therapy considerations and monitoring. The present work addressed the quantification of pharmacokinetic parameters derived from the two-compartment Brix model by analyzing and processing Dynamic Contrast ...
arxiv  

High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]

open access: yes, 2011
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG   +9 more
core   +1 more source

Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

open access: yes, 2015
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip   +2 more
core   +1 more source

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy. [PDF]

open access: yes, 2020
Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric ...
Kraft, Walter K.   +6 more
core   +1 more source

Propofol and children--what we know and what we do not know. [PDF]

open access: yes, 2011
The pharmacokinetics of propofol are relatively well described in the pediatric population. Recent work has confirmed the validity of allometric scaling for predicting propofol disposition across different species and for describing pediatric ontogenesis.
Rigby-Jones, AE, Sneyd, JR
core   +2 more sources

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

On inconsistencies in passive pharmacokinetics [PDF]

open access: yesarXiv, 2011
Some inconsistencies in the passive pharmacokinetics has been observed many years ago. It is possible these inconsistencies result from the lack of proper evolution equations. In this communication, this possibility is illustrated on the example of an evolution equation for an one compartment model.
arxiv  

Pharmacokinetics of gamithromycin in pigs [PDF]

open access: yes, 2012
Objectives : Gamithromycin, a 15-membered semi-synthetic macrolide antibiotic of the azalide subclass, has recently been developed for the treatment and prevention of bovine respiratory disease (BRD).
Croubels, Siska   +6 more
core   +1 more source

Pharmacokinetics of Cannabinoids

open access: yesPain Research and Management, 2005
Delta‐9‐tetrahydrocannabinol (Δ‐9‐THC) is the main psychoactive ingredient of cannabis (marijuana). The present review focuses on the pharmacokinetics of THC, but also includes known information for cannabinol and cannabidiol, as well as the synthetic marketed cannabinoids, dronabinol (synthetic THC) and nabilone.
openaire   +4 more sources

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

open access: yesAdvanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang   +5 more
wiley   +1 more source

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