Results 111 to 120 of about 361,016 (249)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

PHARMACOKINETICS OF MIDAZOLAM IN ANAESTHETIZED CIRRHOTIC PATIENTS

, 1988
Jean‐Hugues Trouvin, Robert Farinotti, J.P. Haberer, F. Servin, M. Chauvin, P. Duvaldestin   +5 more
openalex   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Pharmacokinetics of tenidap sodium administered with food or antacid in healthy volunteers. [PDF]

, 1995
PE Coates, R Mesure
openalex   +1 more source

High‐Concentration Antibody Formulation via Solvent‐Based Dehydration

Advanced Materials, EarlyView.
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng, Lucas Attia, Janet Teng, Patrick S. Doyle   +3 more
wiley   +1 more source

Pharmacokinetics of Re-188-nanodiamonds complex in mice bearing experimental Ehrlich carcinoma [PDF]

, 2017
В. М. Петриев, В. К. Тищенко, Alesya Mikhailovskaya, A.G. Konoplyannikov   +3 more
openalex   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual‐Stage Morphing and Drug Release

Advanced Materials, EarlyView.
A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu, Harischandra Potthuri, Alejandro Sosnik, Luai R. Khoury   +3 more
wiley   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Pharmacokinetics of inorganic cobalt and a vitamin B ₁₂ supplement in the Thoroughbred horse: Differentiating cobalt abuse from supplementation

, 2017
Lynn Hillyer, Z. Ridd, Susanna Fenwick, Pamela Hincks, Stuart W. Paine   +4 more
openalex   +2 more sources

286P Efficacy, safety and pharmacokinetics (PK) of enzalutamide (ENZ) vs placebo (PL) in chemotherapy-naïve patients (pts) with progressive metastatic castration-resistant prostate cancer (mCRPC): An Asian multinational study [PDF]

, 2016
D. Ye, Hyunsu Ahn, Yeong‐Shiau Pu, Weixin Han, L-P. Xie, S-P. Huang, Hui-Ching Wu, Li Ma, Junying Qi, Fang Zhou, Guangxi Sun, L. Chen, Xue Bai, Shunsuke Yamada, Moeko Saito, Kenji Suga, Yongbing Sun   +16 more
openalex   +1 more source