Results 241 to 250 of about 905,269 (391)

Clinical Pharmacokinetics and Safety of High Doses of Ceforanide (BL-S786R) and Cefazolin [PDF]

, 1979
Robert D. Smyth, Morris Pfeffer, Aaron Glick Donald, Rachel Harken, G. H. Hottendorf   +4 more
openalex   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

Advanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang, Jianbing Hou, Xin Hu, Nana Hou, Minghao Xu, Yi Du, Jingyang Xu, Yongzhao Wang, Zhuohao Xie, Junbo Shi, Yundong Zhang, Hongjuan Cui   +11 more
wiley   +1 more source

Pharmacokinetics of Cefaclor and Cephalexin: Dosage Nomograms for Impaired Renal Function [PDF]

, 1978
Daniel A. Spyker, Bruce L. Thomas, Merle A. Sande, W. Kline Bolton   +3 more
openalex   +1 more source

Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications.

British Journal of Clinical Pharmacology, 2003
A. Mangoni, Stephen H. D. Jackson
semanticscholar   +1 more source

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

A Randomized, Open-Label, Single-Dose, Parallel-Group Bioequivalence Study of Ferric Carboxymaltose Injection Under Fasting Conditions in Chinese Adult Subjects With Iron Deficiency Anemia. [PDF]

Pharmacol Res Perspect
Gong F, Hu S, Yuan J, Song J.
europepmc   +1 more source

The science of responsible drinking [PDF]

, 2018
Maskell, Peter D.
core  

In Vitro Activity and Pharmacokinetics in Patients of Cefamandole, a New Cephalosporin Antibiotic

, 1975
Natalie K. Shemonsky, Jaime Carrizosa, Matthew E. Levison   +2 more
openalex   +1 more source

Strategic Design of Aptamer‐Guided Aggregation‐Induced Emission Nanoparticles for Targeted Photodynamic Therapy in Breast Cancer

Advanced Science, EarlyView.
This study presents MF3Ec‐TBPP nanoparticles for targeted photodynamic therapy of Luminal A breast cancer. These nanoparticles combine an AIE‐based photosensitizer with an aptamer. Tests show they effectively inhibit tumor growth while protecting healthy tissue via aggregation and dipalmitoylphosphatidylcholine, indicating potential for improved ...
Charlie C. H. Ma, Qingqing Liu, Yue Sui, Wutong Du, Kristy W. K. Lam, Jacky W. Y. Lam, Chao Li, Tengteng Chen, Jianwei Sun, Nuomin Li, Ryan T. K. Kwok, Jianping Chen, Feiyi Sun, Ben Zhong Tang   +13 more
wiley   +1 more source

The pharmacokinetics effects of the MCAO model on senkyunolide I in pseudo germ-free rats after oral co-administration of Chuanxiong and warfarin. [PDF]

Front Pharmacol
Li H, Li F, Zhou Y, Xiang Z, Zhou B, Lan B, Ruan X.   +6 more
europepmc   +1 more source