Results 191 to 200 of about 5,164,203 (303)

Chemical Constituents, Pharmacological Activities, and Cardiovascular Protective Mechanisms of <i>Dendrobium</i> Species: A Review. [PDF]

Int J Mol Sci
Hu Y, Li Z, Li J, Li X, Wang M.
europepmc   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

<i>Elymus repens</i> (L.) Gould Phytochemistry Pharmacological Activities and Therapeutic Potential with Future Perspectives. [PDF]

Int J Mol Sci
Saparkhanovich ZK, Asilbekovna SE, Ilyasovna TM, Mutalievna AR, Kasymbekovna SZ, Zhanburbaevna UG, Dauletkyzy SZ, Beybitkyzy MA, Yermekuly KN, Zulpidinovich AM, Mukhankyzy ZG.   +10 more
europepmc   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

The phytochemistry and pharmacological activities of <i>Clinacanthus nutans</i> (Burm. f.) Lindau: current evidence, mechanistic insights, and future therapeutic perspectives. [PDF]

Front Pharmacol
Si W, Sun X, Han Y, Zhang Y, Li W, Wei Q, Liu Q, Khan MZ, Zhao X, Liu W.   +9 more
europepmc   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

<i>Cirsium arvense</i> (L.) Scop.: Phytochemistry, Traditional Uses, Pharmacological Activities, and Future Therapeutic Potential. [PDF]

Plants (Basel)
Zhakipbekov KS, Ashirov MZ, Umurzakhova GZ, Kapsalyamova EN, Omirbayeva AY, Kayupova FE, Zhumalina KZ, Ibragimova AG, Serikbayeva EA, Bakytzhanova AB, Farkhatova AD.   +10 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Green Extraction of Bioactive Compounds from Marine Macroalgae: Chemistry, Pharmacological Activities, and Biotechnological Applications. [PDF]

Mar Drugs
Guan Y, Guo Y, Lin L, Zhang L, Chen W, Zhao C.   +5 more
europepmc   +1 more source