Results 261 to 270 of about 5,164,203 (303)
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The pharmacological activity of fish venoms
Toxicon, 2002Venomous creatures have been the source of much recent research in the effort to find novel physiological tools and pharmaceuticals. However, due to the technical difficulties with obtaining and storing venom extracts, the venoms of marine animals, particularly fish, remain a largely untapped source of novel compounds.
Jarrod E, Church, Wayne C, Hodgson
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Prolonged Pharmacologic Activity of Neuroleptics
Archives of General Psychiatry, 1985To the Editor.— Many clinical and laboratory experiments are undertaken on the assumption that tissue levels or effects of neuroleptic agents have cleared by the time of investigation. A review of pertinent studies that appeared in theArchivesduring the 1984 indicates that the typical interval between discontinuing neuroleptic treatment and starting a
A, Campbell, R J, Baldessarini
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Pharmacological activities of dehydroepiandrosterone: A review
Steroids, 2020Dehydroepiandrosterone (DHEA) is a steroidal hormone secreted by Zonareticularis of the adrenal cortex with a characteristic age related pattern of secretion. These hormones are inactive precursors that are transformed into active sex steroids in peripheral target tissues. These hormones are used for the energy, vitality and the natural support of most
Poonam, Sahu +2 more
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Bactericidal activity and pharmacology of flucloxacillin
The American Journal of the Medical Sciences, 1976Flucloxacillin, a recent addition to the group of isoxazolyl penicillins, was studied in vitro and in normal volunteers. The bactericidal activity of the drug against most strains of gram-positive bacteria including penicillin-resistant Staphylococcus aureus was similar to that of oxacillin and approximately fourfold greater than that of cloxacillin ...
M G, Bergeron +3 more
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A pharmacologically active derivative of tetrodotoxin
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1975Abstract Tetrodotoxin, a selective inhibitor of the sodium channel in excitable tissues, has been modified to give two derivatives, one of which retains considerable physiological activity.
R Y, Tsien +4 more
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Pharmacological activity of Terminalia chebula
China Journal of Chinese Materia Medica, 2016Terminalia chebula Retz, known as the "king" of Mongolian and Tibetan medicines, is a drug for a wide range of diseases. The main chemical components of myrobalan include triterpene acid, galloyl glucose, anthraquinonoid. The modern pharmacological studies show that myrobalan has multiple biological activities, including antimicrobial, anti ...
Xiu-Juan, Zhang +3 more
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Pyrrolobenzodiazepines with antinociceptive activity: synthesis and pharmacological activities
European Journal of Medicinal Chemistry, 1995Summary The synthesis of some N-[2-(1H-pyrrol-1-yl)benzyl]arylacetamides and new 4-arylmethyl-5,6-dihydro-4H-pyrrolo[1,2-a]-[1,4]benzodiazepines as their conformationally restricted analogues is reported. The reduction of arylacetamides and N-methylation of pyrrolobenzodiazepines led to the corresponding N-[2-(lH-pyrrol-1-yl)benzyl]arylethylamines ...
MAI, Antonello +7 more
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ATPase activity of pharmacological preparations
European Journal of Pharmacology, 1972Abstract The ATPase activity of pharmacological preparations was tested in phosphate buffer to determine if the breakdown products of ATP contribute significantly to the responses observed to externally applied ATP. Large masses of tissues rapidly broke down ATP whereas the arterial preparations were the most active per unit mass.
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Plasminogen Activators: Pharmacology and Therapy
Radiology, 1990Biochemical advances are providing new insights into coagulation and fibrinolysis. Integrating this biochemical knowledge into plasminogen activator therapy improves understanding of currently available enzymes. Basic components of the fibrinolytic system are discussed and the chemical structures, pharmacokinetics, dosages, and modes of delivery of ...
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Pharmacological Inhibition of Uterine Activity
Acta Obstetricia et Gynecologica Scandinavica, 1982Abstract.Several drugs have been used clinically to inhibit uterine activity in preterm labor, e.g. prostaglandin synthetase inhibitors, β‐receptor agonists, ethanol, calcium antagonists, magnesium sulfate and progesterone. A short review is given of the excitation‐contraction‐relaxation processes in uterine smooth muscle, and the effects and possible ...
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