Translational and clinical development of therapeutic siRNA and ASOs: current industry practices, perspectives, and recommendations. [PDF]
Christensen JK+37 more
europepmc +1 more source
The modular, versatile, and standardized cartridge‐based culture module allows to replicate gut and vascular barriers. Its conventional handling requirements facilitate adoption by non‐technical users, while the design allows safe manipulation and retrieval of samples for permeability assays and endpoint analysis.
Lorenzo Pietro Coppadoro+6 more
wiley +1 more source
Structured oral clinical assessment for pharmacotherapy competencies in medical education: a study of validity and reliability analyses of seven domains. [PDF]
Purba AKR+4 more
europepmc +1 more source
Smart Sampling Capsule for Capture and Detection of Enteric Pathogens in the Small Intestine
An ingestible smart sampling capsule for capturing asymptomatic enteric pathogens at their primary sites of interaction within the small intestine. This capability enables non‐invasive detection of early pathogen colonization within the gut environment prior to fecal shedding, providing a robust approach for pathogen surveillance and microbiome studies.
Akshay Krishnakumar+6 more
wiley +1 more source
Ultrasound‐Powered, Battery‐Free Implants via Triboelectric Energy Harvesting
Ultrasound‐driven triboelectric nanogenerators (US‐TENGs) present a promising approach to battery‐free implants by combining body‐safe ultrasound with the material and structural versatility of TENGs. This review categorizes current US‐TENG research into long‐term and transient short‐term applications and discusses key challenges in materials, device ...
Youngwook Chung+5 more
wiley +1 more source
Correction: Novel mitophagy inducer TJ0113 alleviates pulmonary inflammation during acute lung injury. [PDF]
Liu Z+5 more
europepmc +1 more source
Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka+5 more
wiley +1 more source
Using Relative Infant Dose to Assess Drug Exposure in Breastfed Infants. [PDF]
Spigset O.
europepmc +1 more source
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen+3 more
wiley +1 more source
Editorial: Advances in pharmacotherapy for alcohol use disorder: from mechanisms to clinical interventions. [PDF]
Mangieri RA+3 more
europepmc +1 more source