Results 61 to 70 of about 839,683 (307)

Clinical Pharmacology

open access: yesBritish Journal of Clinical Pharmacology, 2003
P. N. Bennett & M. J. Brown 
Published by Churchill Livingstone, Edinburgh 
ISBN 0‐443‐06480‐6. Price: £39.99.
openaire   +5 more sources

Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics. [PDF]

open access: yes, 2017
Clinical Pharmacology & Therapeutics (CPT) is an established voice of the discipline, a trusted source of new knowledge showcasing discovery, translation, and application of novel therapeutic paradigms to advance the management of patients and ...
Terzic, Andre M., Waldman, Scott A.
core   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

A multi-agent ontologies-based clinical decision support system [PDF]

open access: yesAMINA'2012, Jan 2012, Mahdia, Tunisie, 2020
Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same time, case-based reasoning (CBR) memorizes and returns the experience of solving similar problems.
arxiv  

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy. [PDF]

open access: yes, 2020
Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric ...
Kraft, Walter K.   +6 more
core   +1 more source

Simulated drug administration: An emerging tool for teaching clinical pharmacology during anesthesiology training [PDF]

open access: yes, 2008
A thorough understanding of the dose-response relationship is required for optimizing the efficacy of anesthetics while minimizing adverse drug effects.(1) Nowadays, except for the inhaled anesthetics (for which end-tidal concentrations can be measured ...
De Smet, T.   +2 more
core   +3 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Performance of Clinical Nurse Educators in Teaching Pharmacology and Medication Management: Nursing Students’ Perceptions

open access: yesNursing and Midwifery Studies, 2016
Background Pharmacological knowledge and medication management skills of student nurses greatly depend on the clinical nurse educators’ performance in this critical issue.
Ghamari Zare, Adib-Hajbaghery
doaj   +1 more source

Intensive monitoring studies for assessing medicines : a systematic review [PDF]

open access: yes, 2019
Copyright © 2019 Torre, Cary, Borges, Ferreira, Alarcão, Leufkens, Costa and Martins. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is
Afd Pharmacoepi & Clinical Pharmacology   +9 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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