Results 71 to 80 of about 898,450 (282)

Wy14643 and fenofibrate reduce contractions to hydrogen peroxide in aortae of spontaneously hypertensive rats [PDF]

open access: yes, 2015
The First joint meeting between the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the British Pharmacological Society (BPS) , in association with the Hong Kong Pharmacology Society (HKPS) and the Asia ...
Chen, H, Leung, SWS, Man, RYK
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Can student mental health nurses be prepared for medicines management? [PDF]

open access: yes, 2014
Aim This paper reports on an evaluation of the Medicines with Respect project, which implemented a stepped approach to education and training in medicines management (MM) for mental health nurses (MHNs). Method In the retrospective qualitative study,
Hemingway S   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

CLINICAL PHARMACOLOGY OF DIURETICS

open access: yesJournal of V. N. Karazin Kharkiv National University: Series Medicine, 2014
Clinical pharmacology of diuretics in the international system of ATC (anatomic-therapeutic-chemical) is presented. Classification of this group by the action mechanism and caused effects is provided.
I. V. Soldatenko
doaj  

A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]

open access: yes, 2015
Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
core  

Determination of Influence of Auxiliary Ingredients on Antioxidant Activity of Extract of Leaves of the Quince and Grapes Seed Meal in Phytogel with the Use of Spectrometric Method with the Dpph Indicator System [PDF]

open access: yes, 2017
To study an impact of auxiliary substances on gel containing extracts of quince leaves and grape seed meal, which is based on polymethylsiloxane.Pharmaco - technological and physicochemical methods.
Butska, V. (Victoria)   +3 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Students’ feedback of revised pharmacology record book as a teaching–learning method

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: Pharmacology is taught to medical undergraduates to help them have a firm base in therapeutics, helping them in their future clinical practise.
Dhanya T H, Gopesh Valoth
doaj   +1 more source

Population Pharmacokinetic and Pharmacodynamic Analysis of Buprenorphine for the Treatment of Neonatal Abstinence Syndrome [PDF]

open access: yes, 2017
Neonatal abstinence syndrome (NAS) is a condition affecting newborns exposed to an opioid in utero. Symptoms of NAS include excessive crying, poor feeding, and disordered autonomic control.
Adeniyi-Jones, MD, Susan C.   +4 more
core   +1 more source

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