Results 31 to 40 of about 213,112 (50)

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

open access: yesFrontiers in Oncology, 2019
Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors.
Khalid O. Alfarouk   +24 more
doaj   +1 more source

Effectiveness of team based learning to teach pharmacology for phase-II MBBS students [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2014
Background: TBL (Team based Learning) instructional methods foster applying knowledge in a highly interactive setting. Furthermore, in contrast to PBL (Problem Based Learning), it is a teacher directed method that encourages student- student interaction.
N.K. Hashilkar, M.H. Gelula
doaj  

A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma

open access: yesClinical Case Reports, 2021
Pathogenic germline BRCA2 variants may be associated with an increased risk of hypopharyngeal squamous cell carcinoma that is more responsive to chemoradiation and chemotherapeutics targeting defective double‐strand DNA repair.
Tatiana Correa   +2 more
doaj   +1 more source

Acidification of rat TRPV1 alters the kinetics of capsaicin responses

open access: yesMolecular Pain, 2005
TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C.
Faltynek Connie R   +4 more
doaj   +1 more source

A Swiss army knife for targeting receptors

open access: yeseLife, 2018
A compound can change the activity of NMDA receptors in some regions of a synapse without affecting those in other regions.
Johansen B Amin, Lonnie P Wollmuth
doaj   +1 more source

Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus

open access: yeseLife, 2014
Entry and extrusion of cations are essential processes in living cells. In alkaliphilic prokaryotes, high external pH activates voltage-gated sodium channels (Nav), which allows Na+ to enter and be used as substrate for cation/proton antiporters ...
Paul G DeCaen   +4 more
doaj   +1 more source

NMDA Receptors Subunits, Medical Conditions Involved in, and Their Roles as Drug Targets

open access: yesIberoamerican Journal of Medicine, 2020
In the 1960s, Jeff Watkins and colleagues discovered N-methyl-d-aspartate (NMDA) receptors, and since then, it has been a pharmacodynamic target for many neurological and psychiatric drugs.
Mohamed Omer
doaj   +1 more source

Selectivity and Maximum Response of Vibegron and Mirabegron for β3-Adrenergic Receptors

open access: yesCurrent Therapeutic Research, 2022
: Background: The β3-adrenergic agonists vibegron and mirabegron have shown favorable safety profiles and efficacy for the treatment of overactive bladder.
Benjamin M. Brucker, MD   +3 more
doaj  

Traditional Uses, Pharmacological Efficacy, and Phytochemistry of Moringa peregrina (Forssk.) Fiori. —A Review

open access: yesFrontiers in Pharmacology, 2018
Moringa is a sole genus of Moringaceae family with 13 species distributed in the tropical and sub-tropical regions. Among them, Moringa peregrina is one of the species which has wide range of traditional, nutritional, industrial, and medicinal values ...
Annadurai Senthilkumar   +4 more
doaj   +1 more source

Management of chronic pain after hernia repair

open access: yesJournal of Pain Research, 2018
Kristoffer Andresen, Jacob Rosenberg Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark Abstract: Chronic pain following inguinal hernia repair is a common problem and feared complication. Up to 16% of people experience
Andresen K, Rosenberg J
doaj  

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