Results 181 to 190 of about 37,292 (264)

Identification of a Quinolone-Based Scaffold as a Dual SARS-COV-2 PLᵖʳᵒ and Mᵖʳᵒ Inhibitor: An Integrated Molecular Modeling and In-vitro Evaluation Approach. [PDF]

Drug Des Devel Ther
Atatreh N, Bustanji L, Ferreira JC, Rabeh WM, Mahgoub RE, Ghattas MA.   +5 more
europepmc   +1 more source

Discovery of Novel Molecular Scaffolds to Overcome <i>Pseudomonas aeruginosa</i> Aminoglycoside Resistance: Insights for a Consensus Scoring Rational Design Approach. [PDF]

Int J Mol Sci
Iesce F, Nelen J, Rodríguez-Martínez A, Martínez-Cortés C, Minnelli C, Mobbili G, Di Gregorio A, Vignaroli C, Pérez-Sánchez H, Galeazzi R.   +9 more
europepmc   +1 more source

Pharmacophore-Based Identification and Molecular Characterization of Potent Neprilysin Inhibitors: Biochemical and Therapeutic Implications for Cardiovascular Diseases. [PDF]

Chem Biol Drug Des
Kuo CT, Wu YC, Li JM, Ju TC, Tseng TS.
europepmc   +1 more source

Screening of peptide inhibitors targeting YAP-TEAD4 interaction: affinity evaluation and anti-AML cell activity. [PDF]

J Enzyme Inhib Med Chem
Yang X, Yang S, Lin G, Chen S, Jiang H, Wang Y, Zhang Y, Zhang X.   +7 more
europepmc   +1 more source

Rescuing TP53 from nonsense: novel triazoles for translational readthrough via optimized drug design. [PDF]

Sci Rep
Ricci D, Menditto M, Culletta G, Tutone M, Rizzo C, Pace A, Lentini L, Pibiri I.   +7 more
europepmc   +1 more source

Molecular LEGION: incalculably large coverage of chemical space around the NLRP3 target. [PDF]

Sci Data
Zagribelnyy B, Aladinskiy V, Bondarev N, Ilin I, Malkov M, Vasileva A, Ding X, Lin A, Shayakhmetov R, Aliper A, Ren F, Zhavoronkov A.   +11 more
europepmc   +1 more source

Structure-Based Drug Design Targeting Topoisomerase II Alpha: Discovery of Potential Antitumor Xanthone Derivatives. [PDF]

Molecules
Le TTH, Nguyen TNH, Pham MQ, Tran TTT, Dinh TT, Tran THV, Tran VL, Pham QL.   +7 more
europepmc   +1 more source

Development of an Optimized CXCR4-Targeting Theranostic Pair. [PDF]

J Nucl Med
Kwon D, Bloise I, Zhang Z, Colpo N, Wilson R, Tan R, Merkens H, Zeisler J, Lau J, Lin KS, Bénard F.   +10 more
europepmc   +1 more source

Identification of small molecule inhibitors for the Brachyspira pilosicoli glutamate racemase (Bp-MurI) enzyme using a computational and experimental approach. [PDF]

Sci Rep
Kant R, Ragione R, Christodoulides M.
europepmc   +1 more source

Spatial relationships between the pharmacophores of endomorphin-2: a comparative study of stereoisomers

Open Chemistry, 2012
Leitgeb Balázs
doaj   +1 more source