Results 221 to 230 of about 37,292 (264)
Some of the next articles are maybe not open access.
Conformations and 3D pharmacophore searching
Drug Discovery Today: Technologies, 2010Several methods have been developed and published over the past years to generate sets of diverse and pharmacologically relevant conformations which can be used within 3D pharmacophore search protocols to increase the number of meaningful hits of such experiments.
openaire +2 more sources
Pharmacophore-Based Virtual Screening
Current Medicinal Chemistry, 2008Virtual screening (VS) is an important component of cheminformatics and molecular modeling. An abundance of structural information, indicated by both the ever-increasing availability of 3-dimensional (3D) protein structures and the readiness of free conformational databases of commercially available compounds, such as ZINC, supplies a broad platform ...
openaire +2 more sources
Pharmacophore-Based Virtual Screening
2010This chapter is a review of the most recent developments in the field of pharmacophore modeling, covering both methodology and application. Pharmacophore-based virtual screening is nowadays a mature technology, very well accepted in the medicinal chemistry laboratory. Nevertheless, like any empirical approach, it has specific limitations and efforts to
openaire +2 more sources
Pharmacophore Features of Potential Drugs
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire +2 more sources
Drug Design by Pharmacophore and Virtual Screening Approach
Pharmaceuticals, 2022Deborah Giordano +2 more
exaly
Pharmacophore modeling in drug design
A successful and expanded area of computational drug design is pharmacophore modeling. A pharmacophore is a description of the structural features of a compound that are essential to its biological activity. The rational design of new drugs has made extensive use of the pharmacophore concept.Yasmin, Momin, Vilas, Beloshe
openaire +2 more sources