Results 71 to 80 of about 32,420 (200)

Safety and Effectiveness of Pharmacy Compounded Chenodeoxycholic Acid Capsules for Patients With Cerebrotendinous Xanthomatosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Chenodeoxycholic acid (CDCA) is an essential drug for patients with rare metabolic disease cerebrotendinous xanthomatosis (CTX). To ensure continuation of treatment, the Amsterdam UMC hospital pharmacy developed pharmacy compounded CDCA capsules when the authorized CDCA capsules were no longer available for Dutch patients.
Natalja Bouwhuis, Soumia Majait, Yasmin Polak, Aylene de Jong, Bart A. W. Jacobs, Frédéric M. Vaz, Willemijn G. Leen, E. Marleen Kemper, Eleonora L. Swart, Carla E. M. Hollak   +9 more
wiley   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

The Cinderella tree, Quillaja saponaria – A soap story

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 439-451, March 2026.
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, Volume 22, Issue 16, 17 March 2026.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Effects of environmental factors on genetic diversity in the endangered Notopterygium incisum from the southeastern Qinghai–Tibetan Plateau

Plant Species Biology, Volume 41, Issue 2, March 2026.
This study focuses on 38 populations of Notopterygium incisum from its main distribution areas (Sichuan Province, Gansu Province, and Qinghai Province), conducting molecular genetic diversity analysis and investigating the correlations between genetic variation and climatic variables, geographical distribution, and elevation gradients.
Jinqiu Liao, Ao Luo, Rui Zeng, Xianhong Feng, Yuanyuan Jiang, Xuexue Deng, Li Zhang, Ruiwu Yang   +7 more
wiley   +1 more source

Making the Old New Again Through the Process of Recombinant Innovation

Journal of Product Innovation Management, Volume 43, Issue 2, Page 290-312, March 2026.
ABSTRACT Academic Summary Recombinant innovation—the process through which atypical and unexpected combinations of knowledge generate novel outcomes—is a critical driver of organizational distinctiveness and market transformation. While prior research has focused on firm‐ and industry‐level mechanisms, less attention has been given to multilevel ...
Vittoria Magrelli, Josip Kotlar, Alfredo De Massis, Federico Frattini, Antonio Messeni Petruzzelli   +4 more
wiley   +1 more source

Repurposing Drugs as Bacteroides fragilis BFT‐3 Inhibitors in the Animal Infection Model Galleria mellonella

Annals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
This work establishes a newly developed Galleria mellonella infection model as a powerful, ethical platform for studying Bacteroides fragilis pathogenesis and therapy. Leveraging this model, the study identifies MOA4 as a potent BFT‐3 inhibitor that improves host survival, increases bacterial clearance, and synergizes with antibiotics without toxicity.
Ana Jiménez‐Alesanco, Marta Gómara‐Lomero, Hajar Jeblaoui, Sonia Vega, Adrián Velázquez‐Campoy, José Antonio Aínsa, Olga Abián   +6 more
wiley   +1 more source

Pharmacognostical and Analytical Standards of Dioscorea Esculenta Burkill.

Journal of Research in Traditional Medicine, 2017
Background: Dioscoria species is a Kanda Shakha (tuberous vegetable) useful as vegetable and grows abundantly around Udupi district, Karnataka, India. Dioscorea esculenta Burkill is one of the rare and costly tuber cultivated in very few areas of Udupi ...
Tapankumar H. Gandhi, Rohit Gokarn, Sunil Kumar K N, Ravikrishna A S, Bairy T Shridhar   +4 more
doaj  

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

Safety of 3′‐sialyllactose (3′‐SL) sodium salt produced with a derivative strain (Escherichia coli K‐12 MG1655 INB‐3SL_01) of E. coli K‐12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 3, March 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 3′‐sialyllactose (3′‐SL) sodium salt as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) 3′‐SL (sodium salt),
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Thomas Frenzel, Harry J. McArdle, Peter Moldeus, Monika Neuhäuser‐Berthold, Josef Rudolf Schlatter, Henk van Loveren, Estefanía Noriega Fernández, Karen Ildico Hirsch‐Ernst   +23 more
wiley   +1 more source