Results 21 to 30 of about 2,739,138 (153)

Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis

Experimental Hematology & Oncology, 2022
Background Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear.
Xiaoman Li, Qi Jia, Yinyin Zhou, Xuan Jiang, Li Song, Yuanyuan Wu, Aiyun Wang, Wenxing Chen, Shijun Wang, Yin Lu   +9 more
doaj   +1 more source

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments

Chinese Medicine, 2023
Background Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly understood.
Haojia Wang, Zhishan Wu, Xiaotian Fan, Chao Wu, Shan Lu, Libo Geng, Antony Stalin, Yingli Zhu, Fanqin Zhang, Jiaqi Huang, Pengyun Liu, Huiying Li, Leiming You, Jiarui Wu   +13 more
doaj   +1 more source

GCIP attenuates DOCA/salt-induced cardiac hypertrophy and fibrosis in mice

Di-san junyi daxue xuebao, 2022
Objective To determine the effects of improvement of G alpha q-protein carboxyl terminus imitation polypeptide (GCIP) on deoxycorticosterone acetate (DOCA)/salt-induced cardiac hypertrophy and fibrosis in mice.
TANG Kecheng, LIU Qiao, YANG Shengqian, ZHONG Bin, LUO Qingman, LI Xiaohui   +5 more
doaj   +1 more source

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

Nature Communications, 2018
The metabolic regulator protein family, mTOR, regulate natural killer (NK) cell development and function, but the underlying mechanism is unclear. Here, the authors show that Raptor/mTORC1 and Rictor/mTORC2 form a feedback crosstalk network to variegate ...
Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng   +19 more
doaj   +1 more source

A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence

Frontiers in Pharmacology, 2020
Clinically, the treatments against asthma like β2 agonist focus on controlling the symptoms rather than inhibiting recurrence radically. This study aims to evaluate the efficacy and mechanism of a potent Chinese prescription Yu-Ping-Feng-San (YPFS ...
Kaifan Bao, Weiyuan Yuan, Yijing Zhou, Yanyan Chen, Xuerui Yu, Xiaoyu Wang, Zhirong Jia, Xi Yu, Xiaotong Wang, Lu Yao, Siqi Wang, Yifan Xu, Yuheng Zhang, Jie Zheng, Min Hong   +14 more
doaj   +1 more source

Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder

Cell Communication and Signaling, 2023
The association between capsaicin, the major natural pungent compound of chili peppers, and gastric cancer progression has engendered conflicting findings.
Rui Deng, Suyun Yu, Xingqiu Ruan, Huan Liu, Gangfan Zong, Peng Cheng, Ruizhi Tao, Wenxing Chen, Aiyun Wang, Yang Zhao, Zhonghong Wei, Yin Lu   +11 more
doaj   +1 more source

Investigation on the efficiency of Brucea javanica oil emulsion injection with chemotherapy for treating malignant pleural effusion: A meta-analysis of randomized controlled trials

Frontiers in Pharmacology, 2022
Introduction: Systematic evaluation of the clinical efficacy and safety of Brucea javanica oil emulsion injection (BJOEI) in combination with chemotherapy in the treatment of malignant pleural effusion (MPE).Methods: The study searched CNKI, Wanfang ...
Rui Shi, Zhishan Wu, Haojia Wang, Jingyuan Zhang, Fanqin Zhang, Antony Stalin, Meilin Chen, Jiaqi Huang, Yiyan Zhai, Qianqian Zhang, Pengyun Liu, Jiarui Wu, Bin Sun, Chunfang Wu   +13 more
doaj   +1 more source

Rotation Effects on the Target-Volume Margin Determination [PDF]

Physica Medica (2014), 2014
Rotational setup errors are usually neglected in most clinical centers. An analytical formula is developed to determine the extra margin between clinical target volume (CTV) and planning target volume (PTV) to account for setup errors. The proposed formula corrects for both translational and rotational setup errors and then incorporated into margin ...
arxiv   +1 more source

Corrigendum: Revealing the mechanism of Huazhi Rougan granule in the treatment of nonalcoholic fatty liver through intestinal flora based on 16S rRNA, metagenomic sequencing and network pharmacology

Frontiers in Pharmacology, 2023
Graphical ...
Yingying Liu, Yingying Tan, Jiaqi Huang, Chao Wu, Xiaotian Fan, Antony Stalin, Shan Lu, Haojia Wang, Jingyuan Zhang, Fanqin Zhang, Zhishan Wu, Bing Li, Zhihong Huang, Meilin Chen, Guoliang Cheng, Yanfang Mou, Jiarui Wu   +16 more
doaj   +1 more source

Mass enhancement in narrow band systems [PDF]

Journal of Physics: Condensed Matter Vol.12, p.2783 (2000), 2000
A perturbative study of the Holstein Molecular Crystal Model which accounts for lattice structure and dimensionality effects is presented. Antiadiabatic conditions peculiar of narrow band materials and an intermediate to strong electron-phonon coupling are assumed.
arxiv   +1 more source