Results 21 to 30 of about 88,845 (204)

Cereals of antiquity and early Byzantine times. Wheat and barley in medical sources (second to seventh centuries AD) [PDF]

open access: yes, 2014
The present book aims at a detailed analysis of the evolution of dietetic doctrines and an assessment of the value of medical sources for historians of food.
Jagusiak, Krzysztof   +2 more
core   +1 more source

Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis

open access: yesNatural Products and Bioprospecting
Thrombosis triggers various severe diseases, while antithrombotic drugs carry bleeding risks, making the development of novel natural anticoagulants a subject of widespread attention.
Han-xue Zheng   +6 more
doaj   +1 more source

Old School Catalog 1924-25, The School of Pharmacy [PDF]

open access: yes, 1924
https://scholar.valpo.edu/oldschoolcatalogs/1001/thumbnail ...
Valparaiso University
core   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo   +15 more
wiley   +1 more source

Old School Catalog 1921-22, The School of Pharmacy [PDF]

open access: yes, 1921
https://scholar.valpo.edu/oldschoolcatalogs/1089/thumbnail ...
Valparaiso University
core   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis

open access: yesCell Death and Disease, 2021
Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder characterized by recurrent eczematous lesions. Interleukin (IL)−33, a cytokine of the IL-1 family, was found to play an important role in the pathogenesis of AD.
Jie Zheng   +7 more
doaj   +1 more source

Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network Pharmacology

open access: yesFrontiers in Pharmacology, 2022
Graphical ...
Yingying Liu   +16 more
doaj   +1 more source

Old School Catalog 1909-10, Chicago College of Medicine and Surgery [PDF]

open access: yes, 1909
https://scholar.valpo.edu/oldschoolcatalogs/1019/thumbnail ...
Valparaiso University
core   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

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