Results 41 to 50 of about 84,446 (125)

Tubocapsenolide A Overcomes Oxaliplatin Resistance in Colorectal Cancer by Targeting PLK1 to Impair CEP55–ESCRT‐Associated Vesicular Damage Clearance

Advanced Science, EarlyView.
Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang, Jing Liang, Lu Wang, Hongyan Zhang, Zhiruo Zhang, Yang Liu, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Hua Li, Lixia Chen   +15 more
wiley   +1 more source

Based on Systematic Pharmacology: Molecular Mechanism of Siwei Jianbu Decoction in Preventing Oxaliplatin-Induced Peripheral Neuropathy

Neural Plasticity, 2020
Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect caused by chemotherapy drugs, and its existence seriously affects the quality of life of patients.
Peng Zhang, Yuting Lu, Chao Yang, Qiuyan Zhang, Yangyan Qian, Jinshuai Suo, Peng Cheng, Jing Zhu   +7 more
doaj   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

Materia Medica and Pharmacy.

JAMA: The Journal of the American Medical Association, 1906
Mode of access: Internet.
openaire   +2 more sources

Muzej za povijest farmacije Farmaceutskog fakulteta Univerziteta u Beogradu [PDF]

, 2009
History of Pharmacy Museum at the Faculty of Pharmacy University of Belgrade was founded in Belgrade in 1952, thanks to many pharmacists and historians, but especially to Mr Andrija Mirkovicacute; (Mpharm). His precious private collection of antiquities,
Kerničan, Leontina, Krajnović, Dušanka   +1 more
core   +5 more sources

Medical botany

, 1897
"Presented to the Section on Materia Medica, Pharmacy and Therapeutics, at the forty-eighth annual meeting of the American Medical Association, held at Philadelphia, Pa., June 1-4, 1897.Reprinted from Journal of the American Medical Association. Sept. 4,
William Trelease, Trelease, William, 1857-1945, Trelease, William, 1857-1945.   +2 more
core   +1 more source

Pharmacy, Testing and the Language of Truth in Renaissance Italy [PDF]

, 2017
This article examines the role of testing and innovation in sixteenthcentury Italian pharmacy. I argue that apothecaries were less concerned with testing drugs for efficacy or creating novel products than with reactivating an older Mediterranean ...
Valentina Pugliano
core   +2 more sources

Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells

Chinese Medicine
Background Radiotherapy can damage hematopoietic stem cells (HSC) in bone marrow, leading to impaired hematopoietic function. Current treatments mainly target differentiated hematopoietic progenitor cells, which may accelerate their depletion ...
Ling Zhang, Wanqi Xu, Yueying Zeng, Long Wang, Jiesi Luo, Xiaogang Zhou, Qibing Mei, Dalian Qin, Anguo Wu, Jianming Wu, Feihong Huang   +10 more
doaj   +1 more source

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

BMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao, Xiangwei Lv, Miaomiao Zhang, Jiayi Liu, Yun Chen, Yunna Li, Gaoyuan Liu, Fuming Yang, Ziqiang Han, Yunyun Wei   +9 more
wiley   +1 more source

Leighton F. Appleman, (portrait) ca. 1904-1932

, 1932
1897 graduate of Jefferson Medical College. Demonstrator of Pharmacy and Materia Medica, Jefferson Medical College, 1904-1932.https://jdc.jefferson.edu/historical_photos/1004/thumbnail ...

core   +1 more source